Small RNA研究

国内学者使用康成Small RNA相关服务发表的SCI成果

tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. Signal Transduction and Targeted Therapy. 2023 NEW!

Cell-Free Osteoarthritis Treatment with Sustained-Release of Chondrocyte-Targeting Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells to Rejuvenate Aging Chondrocytes. ACS nano. 2023 NEW!

piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination. Experimental & Molecular Medicine. 2023 NEW!

PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer. Cell Death Discovery. 2024 NEW!

A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes Journal of hematology & oncology . 2022

A novel 3’tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer  Cell Death & Disease . 2022

tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner  Journal of Experimental & Clinical Cancer Research . 2022

Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis . Cell Death & Disease . 2022

Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex . Cell Reports . 2022

TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis  iScience . 2022

Maternal genetic effect on apoptosis of ovarian granulosa cells induced by cadmium. Food and Chemical Toxicology .2022

Cadmium disrupts mouse embryonic stem cell differentiation into ovarian granulosa cells through epigenetic mechanisms  Ecotoxicology and Environmental Safety . 2022

miR-6769b-5p targets CCND-1 to regulate proliferation in cadmium-treated placental trophoblasts: Association with the impairment of fetal growth Ecotoxicology and Environmental Safety . 2022

Identification of Small Nucleolar RNA SNORD60 as a Potential Biomarker and Its Clinical Significance in Lung Adenocarcinoma . BioMed Research International . 2022

A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer  Molecular cancer . 2021

Identification and potential functions of tRNA-derived small RNAs (tsRNAs) in irritable bowel syndrome with diarrhea Pharmacological Research . 2021

Altered sperm tsRNAs in aged male contribute to anxiety‐like behavior in offspring  Aging Cell . 2021

Pathophysiological Significance of Neutrophilic Transfer RNA-Derived Small RNAs in Asymptomatic Moyamoya Disease  Cells . 2021

A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer Journal of Experimental & Clinical Cancer Research . 2021

Genome-wide interrogation of transfer RNA-derived small RNAs in a mouse model of traumatic brain injury  Neural Regeneration Research . 2021

Circulating tRNA-derived small RNAs (tsRNAs) signature for the diagnosis and prognosis of breast cancer  NPJ breast cancer . 2021

A specific tRNA half, 5’tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2 Journal of Experimental & Clinical Cancer Research . 2021

Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells . PLoS genetics . 2021

Glioma glycolipid metabolism: MSI2–SNORD12B–FIP1L1–ZBTB4 feedback loop as a potential treatment target  Clinical and translational medicine . 2021

Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src Signal transduction and targeted therapy . 2021

Diverging targets mediate the pathological role of miR-199a-5p and miR-199-3p by promoting cardiac hypertrophy and fibrosis Molecular Therapy-Nucleic Acids . 2021

Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis  Journal of Experimental & Clinical Cancer Research . 2021

A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone  Molecular Medicine . 2021

Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling  Inflammatory Bowel Diseases . 2021

microRNA Expression Profiles in Myocardium of High-Fat Diet-Induced Obesity Rat . Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy . 2020

A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance . Theranostics . 2020

Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer . Cell Death & Disease . 2020

MiR-107 confers chemoresistance to colorectal cancer by targeting calcium-binding protein 39 . British Journal of Cancer . 2020

ZBTB7A, a miR-663a target gene, protects osteosarcoma from endoplasmic reticulum stress-induced apoptosis by suppressing LncRNA GAS5 expression . Cancer Letters . 2019

PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway . Angiogenesis . 2019

miRNAs deregulation in serum of mice is associated with lung cancer related pathway deregulation induced by PM2. 5 . Environmental Pollution . 2019

Endothelial cell-derived small extracellular vesicles suppress cutaneous wound healing through regulating fibroblasts autophagy . Clinical Science . 2019

Exosomes derived from hypoxic epithelial ovarian cancer cells deliver microRNAs to macrophages and elicit a tumor-promoted phenotype . Cancer letters . 2018

miRNA-3473b contributes to neuroinflammation following cerebral ischemia . Cell death & disease . 2018

circDiaph3 regulates rat vascular smooth muscle cell differentiation, proliferation, and migration . The FASEB Journal . 2018

Circulating miRNA Expression Profiling and Target Prediction in Patients Receiving Dexmedetomidine . Cellular Physiology and Biochemistry . 2018

Identification of miRNA-7 by genome-wide analysis as a critical sensitizer for TRAIL-induced apoptosis in glioblastoma cells. Nucleic acids research. 2017

Combination of AAV-TRAIL with miR-221-Zip Therapeutic Strategy Overcomes the Resistance to TRAIL Induced Apoptosis in Liver Cancer. Theranostics. 2017

Exploring Transcription Factors-microRNAs Co-regulation Networks in Schizophrenia. Schizophrenia Bulletin. 2016

Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma. J Pathol. 2016

Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling. PLos Genetics.  2016

Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis. Cell Death & Disease. 2017

Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer. Cell Death & Disease. 2017

Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer.Cell Death & Disease. 2017

miRNA-3473b contributes to neuroinflammation following cerebral ischemia.Cell Death & Disease. 2017

SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis. Molecular Cancer. 2017

MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI. Cell death & disease. 2018

MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6.Cell death & disease. 2018

Circulating microRNA signature for the diagnosis of childhood dilated cardiomyopathy. Scientific reports. 2018

Increased Variability of Genomic Transcription in Schizophrenia. Scientific Reports. 2016

Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer. Journal of Experimental & Clinical Cancer Research. 2017

MiRNA Expression Profile of the Myocardial Tissue of Pigs with Coronary Microembolization. Cellular Physiology and Biochemistry. 2017

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