P1.02D.02 Tumor-Derived Exosomal tsRNA 3’ tiRNA-AlaCGC Promotes Immune Tolerance by Inducing Fibroblast Senescence in LUAD. Journal of Thoracic Oncology. 2024 NEW!
Faecal hsa-miR-7704 inhibits the growth and adhesion of Bifidobacterium longum by suppressing ProB and aggravates hepatic encephalopathy. npj Biofilms and Microbiomes. 2024 NEW!
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component. Environmental Pollution. 2024 NEW!
PTransfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of bromodulin. Cellular & Molecular Biology Letters. 2024 NEW!
Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of bromodulin. Cellular & Molecular Biology Letters. 2024 NEW!
Xuefu Zhuyu Decoction promotes synaptic plasticity by targeting miR-191a-5p/BDNF-TrkB axis in severe traumatic brain injury. Phytomedicine. 2024 NEW!
U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression. Breast Cancer Research. 2024 NEW!
PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer. Cell Death Discovery. 2024 NEW!
Exosomes from umbilical cord mesenchymal stem cells ameliorate intervertebral disc degeneration via repairing mitochondrial dysfunction. Journal of Orthopaedic Translation. 2024 NEW!
Downregulation of tRF-Cys-GCA-029 by hyperglycemia promotes tumorigenesis and glycolysis of diabetic breast cancer through upregulating PRKCG translation. Breast Cancer Research. 2024 NEW!
Optimizing of a suitable protocol for isolating tissue-derived extracellular vesicles and profiling small RNA patterns in hepatocellular carcinoma. Liver International. 2024 NEW!
Optimizing of a suitable protocol for isolating tissue-derived extracellular vesicles and profiling small RNA patterns in hepatocellular carcinoma. Liver International. 2024 NEW!
miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy. International Immunopharmacology. 2024 NEW!
tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. Signal Transduction and Targeted Therapy. 2023
Cell-Free Osteoarthritis Treatment with Sustained-Release of Chondrocyte-Targeting Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells to Rejuvenate Aging Chondrocytes. ACS nano. 2023
piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination. Experimental & Molecular Medicine. 2023
PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer. Cell Death Discovery. 2024
A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes Journal of hematology & oncology . 2022
A novel 3’tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer Cell Death & Disease . 2022
tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner Journal of Experimental & Clinical Cancer Research . 2022
Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis . Cell Death & Disease . 2022
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex . Cell Reports . 2022
TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis iScience . 2022
Maternal genetic effect on apoptosis of ovarian granulosa cells induced by cadmium. Food and Chemical Toxicology .2022
Cadmium disrupts mouse embryonic stem cell differentiation into ovarian granulosa cells through epigenetic mechanisms Ecotoxicology and Environmental Safety . 2022
miR-6769b-5p targets CCND-1 to regulate proliferation in cadmium-treated placental trophoblasts: Association with the impairment of fetal growth Ecotoxicology and Environmental Safety . 2022
Identification of Small Nucleolar RNA SNORD60 as a Potential Biomarker and Its Clinical Significance in Lung Adenocarcinoma . BioMed Research International . 2022
A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer Molecular cancer . 2021
Identification and potential functions of tRNA-derived small RNAs (tsRNAs) in irritable bowel syndrome with diarrhea Pharmacological Research . 2021
Altered sperm tsRNAs in aged male contribute to anxiety‐like behavior in offspring Aging Cell . 2021
Pathophysiological Significance of Neutrophilic Transfer RNA-Derived Small RNAs in Asymptomatic Moyamoya Disease Cells . 2021
A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer Journal of Experimental & Clinical Cancer Research . 2021
Genome-wide interrogation of transfer RNA-derived small RNAs in a mouse model of traumatic brain injury Neural Regeneration Research . 2021
Circulating tRNA-derived small RNAs (tsRNAs) signature for the diagnosis and prognosis of breast cancer NPJ breast cancer . 2021
A specific tRNA half, 5’tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2 Journal of Experimental & Clinical Cancer Research . 2021
Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells . PLoS genetics . 2021
Glioma glycolipid metabolism: MSI2–SNORD12B–FIP1L1–ZBTB4 feedback loop as a potential treatment target Clinical and translational medicine . 2021
Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src Signal transduction and targeted therapy . 2021
Diverging targets mediate the pathological role of miR-199a-5p and miR-199-3p by promoting cardiac hypertrophy and fibrosis Molecular Therapy-Nucleic Acids . 2021
Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis Journal of Experimental & Clinical Cancer Research . 2021
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone Molecular Medicine . 2021
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling Inflammatory Bowel Diseases . 2021
microRNA Expression Profiles in Myocardium of High-Fat Diet-Induced Obesity Rat . Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy . 2020
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance . Theranostics . 2020
Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer . Cell Death & Disease . 2020
MiR-107 confers chemoresistance to colorectal cancer by targeting calcium-binding protein 39 . British Journal of Cancer . 2020
ZBTB7A, a miR-663a target gene, protects osteosarcoma from endoplasmic reticulum stress-induced apoptosis by suppressing LncRNA GAS5 expression . Cancer Letters . 2019
PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway . Angiogenesis . 2019
miRNAs deregulation in serum of mice is associated with lung cancer related pathway deregulation induced by PM2. 5 . Environmental Pollution . 2019
Endothelial cell-derived small extracellular vesicles suppress cutaneous wound healing through regulating fibroblasts autophagy . Clinical Science . 2019
Exosomes derived from hypoxic epithelial ovarian cancer cells deliver microRNAs to macrophages and elicit a tumor-promoted phenotype . Cancer letters . 2018
miRNA-3473b contributes to neuroinflammation following cerebral ischemia . Cell death & disease . 2018
circDiaph3 regulates rat vascular smooth muscle cell differentiation, proliferation, and migration . The FASEB Journal . 2018
Circulating miRNA Expression Profiling and Target Prediction in Patients Receiving Dexmedetomidine . Cellular Physiology and Biochemistry . 2018
Identification of miRNA-7 by genome-wide analysis as a critical sensitizer for TRAIL-induced apoptosis in glioblastoma cells. Nucleic acids research. 2017
Combination of AAV-TRAIL with miR-221-Zip Therapeutic Strategy Overcomes the Resistance to TRAIL Induced Apoptosis in Liver Cancer. Theranostics. 2017
Exploring Transcription Factors-microRNAs Co-regulation Networks in Schizophrenia. Schizophrenia Bulletin. 2016
Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma. J Pathol. 2016
Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling. PLos Genetics. 2016
Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis. Cell Death & Disease. 2017
Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer. Cell Death & Disease. 2017
Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer.Cell Death & Disease. 2017
miRNA-3473b contributes to neuroinflammation following cerebral ischemia.Cell Death & Disease. 2017
SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis. Molecular Cancer. 2017
MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI. Cell death & disease. 2018
MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6.Cell death & disease. 2018
Circulating microRNA signature for the diagnosis of childhood dilated cardiomyopathy. Scientific reports. 2018
Increased Variability of Genomic Transcription in Schizophrenia. Scientific Reports. 2016
Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer. Journal of Experimental & Clinical Cancer Research. 2017
MiRNA Expression Profile of the Myocardial Tissue of Pigs with Coronary Microembolization. Cellular Physiology and Biochemistry. 2017