The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis . Molecular Cell . 2022 NEW!
Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer . Redox Biology . 2022 NEW!
Role of lncSLCO1C1 in gastric cancer progression and resistance to oxaliplatin therapy . Clinical and Translational Medicine . 2022 NEW!
GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma . Journal of Advanced Research . 2022 NEW!
Hypoxia-induced lncHILAR promotes renal cancer cell invasion and metastasis via ceRNA for the miR-613/206/1-1-3p/Jagged-1/Notch/CXCR4 signaling pathway . Molecular Therapy . 2021
Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy . Cell Death & Differentiation . 2021
The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway . Molecular Cancer . 2022 NEW!
Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p . Molecular Cancer . 2022 NEW!
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC . Molecular cancer . 2021
CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity . Molecular cancer . 2021
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output . Cell . 2020
Extracellular Vesicle-Mediated Delivery of CircSCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models . Circulation . 2020
A Noncoding Regulatory RNAs Network Driven by Circ‐CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma . Hepatology . 2020
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , Molecular Cancer . 2022 NEW!
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer . Molecular Cancer . 2022 NEW!
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis . Cell Death & Differentiation . 2022 NEW!
METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis . Journal of Experimental & Clinical Cancer Research . 2022 NEW!
m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels . Cancer Communications . 2022 NEW!
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression . Oncogene . 2022 NEW!
The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis . American Journal of Respiratory Cell and Molecular Biology . 2022 NEW!
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1 . Theranostics . 2021
ALKBH5-mediated m6A mRNA Methylation Governs Human Embryonic Stem Cell Cardiac Commitment . Molecular Therapy-Nucleic Acids . 2021
ALKBH5 suppresses tumor progression via an m 6 A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma . Cell Death & Disease . 2021
N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1-Regulated Astrocyte Dysfunction and Depressive-like Behaviors. . Biological Paychiatry . 2020
SIRT1 regulates N6‐methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2‐dependent FTO SUMOylation . Hepatology . 2020
DNA hydroxymethylation reprogramming of β-oxidation genes mediates early-life arsenic-evoked hepatic lipid accumulation in adult mice. Journal of Hazardous Materials . 2022NEW!
Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription. Journal of Hepatology . 2021NEW!
Oncogenic role of SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2 positive diffuse large B-cell lymphomas. Blood . 2021NEW!
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain. Nature communications . 2021NEW!
Histone demethylase KDM6A promotes somatic cell reprogramming by epigenetically regulating the PTEN and IL‐6 signal pathways . STEM CELLS . 2020
Multi-generational obesogenic effects of sulfomethoxazole on Caenorhabditis elegans through epigenetic regulation . Journal of Hazardous Materials . 2019
A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes . Journal of hematology & oncology . 2022NEW!
A novel 3’tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer . Cell Death & Disease . 2022NEW!
tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner . Journal of Experimental & Clinical Cancer Research . 2022NEW!
Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis . Cell Death & Disease . 2022NEW!
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex . Cell Reports . 2022NEW!
TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis . iScience . 2022NEW!
Maternal genetic effect on apoptosis of ovarian granulosa cells induced by cadmium. Food and Chemical Toxicology .2022NEW!
Cadmium disrupts mouse embryonic stem cell differentiation into ovarian granulosa cells through epigenetic mechanisms . Ecotoxicology and Environmental Safety . 2022NEW!
miR-6769b-5p targets CCND-1 to regulate proliferation in cadmium-treated placental trophoblasts: Association with the impairment of fetal growth . Ecotoxicology and Environmental Safety . 2022NEW!
Identification of Small Nucleolar RNA SNORD60 as a Potential Biomarker and Its Clinical Significance in Lung Adenocarcinoma . BioMed Research International . 2022NEW!
A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer . Molecular cancer . 2021
Altered sperm tsRNAs in aged male contribute to anxiety‐like behavior in offspring . Aging Cell . 2021
A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer . Journal of Experimental & Clinical Cancer Research . 2021
Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells . PLoS genetics . 2021
Glioma glycolipid metabolism: MSI2–SNORD12B–FIP1L1–ZBTB4 feedback loop as a potential treatment target . Clinical and translational medicine . 2021
Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src . Signal transduction and targeted therapy . 2021
Diverging targets mediate the pathological role of miR-199a-5p and miR-199-3p by promoting cardiac hypertrophy and fibrosis . Molecular Therapy-Nucleic Acids . 2021
Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis . Journal of Experimental & Clinical Cancer Research . 2021
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone . Molecular Medicine . 2021
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling . Inflammatory Bowel Diseases . 2021
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance . Theranostics . 2020
Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer . Cell Death & Disease . 2020
Long non-coding RNA DDX11-AS1 promotes the proliferation and migration of glioma cells by combining with HNRNPC . Molecular Therapy-Nucleic Acids . 2022NEW!
Trehalose Protects Keratinocytes against Ultraviolet B Radiation by Activating Autophagy via Regulating TIMP3 and ATG9A . Oxidative Medicine and Cellular Longevity . 2022NEW!
2, 3, 5, 4’-tetrahydroxy-stilbene-2-O-β-D-glucoside ameliorates NAFLD via attenuating hepatic steatosis through inhibiting mitochondrial dysfunction dependent on SIRT5 . Phytomedicine . 2022NEW!
Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription . Journal of Hepatology . 2021NEW!
Antihypertrophic Memory after Regression of Exercise-induced Physiological Myocardial Hypertrophy is Mediated by the Long Noncoding RNA Mhrt779 . Circulation . 2021
N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression . Molecular cell . 2021
Nidogen1-enriched extracellular vesicles accelerate angiogenesis and bone regeneration by targeting Myosin-10 to regulate endothelial cell adhesion . Bioactive Materials . 2021
A tumor-suppressive circular RNA mediates uncanonical integrin degradation by the proteasome in liver cancer . Science Advances . 2021
Glioblastoma cell–derived lncRNA-containing exosomes induce microglia to produce complement C5, promoting chemotherapy resistance . Cancer immunology research . 2021
Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis . Nature communications . 2019
Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13. 32 accelerates tumorigenesis . Nucleic acids research . 2019