RRFERV stabilizes TEAD1 expression to mediate nasopharyngeal cancer radiation resistance rendering tumor cells vulnerable to ferroptosis. International Journal of Surgery. 2024 NEW!
LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer. Journal of Experimental & Clinical Cancer Research. 2024 NEW!
FOSL1-mediated LINC01566 negatively regulates CD4+ T-cell activation in myasthenia gravis. Journal of Neuroinflammation. 2024 NEW!
LIN28B induced PCAT5 promotes endometrial cancer progression and glycolysis via IGF2BP3 deubiquitination. Cell Death & Disease. 2024 NEW!
Maternal nicotine exposure promotes hippocampal CeRNA-mediated excitotoxicity and social barriers in adolescent offspring mice. Ecotoxicology and Environmental Safety. 2024 NEW!
Histone modifications and Sp1 promote GPR160 expression in bone cancer pain within rodent models. EMBO Rep. 2024 NEW!
N6-methyladenosine modification of lnc-CCKAR-5 regulates autophagy in human umbilical cord mesenchymal stem cells by destabilizing LMNA and inhibits diabetic wound healing. Journal of Investigative Dermatology. 2024 NEW!
Long noncoding RNA AK144717 exacerbates pathological cardiac hypertrophy through modulating the cellular distribution of HMGB1 and subsequent DNA damage response. Cellular and Molecular Life Sciences. 2024 NEW!
Microarray analysis identifies lncFirre as a potential regulator of obesity-related acute lung injury. Life Sciences. 2024 NEW!
Buyang huanwu decoction promotes remyelination via miR-760-3p/GPR17 axis after intracerebral hemorrhage. Journal of Ethnopharmacology. 2024 NEW!
Knockdown of LncRNA Lcn2-204 alleviates sepsis-induced myocardial injury by regulation of iron overload and ferroptosis. Journal of Molecular and Cellular Cardiology. 2024 NEW!
LncRNA PSMB8-AS1 Instigates Vascular Inflammation to Aggravate Atherosclerosis. Circulation Research. 2023
High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA. Signal Transduction and Targeted Therapy. 2023
LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer. Journal of Experimental & Clinical Cancer Research. 2024
A lncRNA signature associated with tumor immune heterogeneity predicts distant metastasis in locoregionally advanced nasopharyngeal carcinoma. Nature Communications. 2023
FAR591 promotes the pathogenesis and progression of SONFH by regulating Fos expression to mediate the apoptosis of bone microvascular endothelial cells. Bone Research. 2023
LncRNA NIPA1-SO confers atherosclerotic protection by suppressing the transmembrane protein NIPA1. Journal of Advanced Research. 2023
Lnc Tmem235 promotes repair of early steroid-induced osteonecrosis of the femoral head by inhibiting hypoxiainduced apoptosis of BMSCs. Experimental & Molecular Medicine. 2022
Mmu-LncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p /HtrA3 signaling axis. Molecular Therapy. 2022
Acylglycerol kinase promotes ovarian cancer progression and regulates mitochondria function by interacting with ribosomal protein L39. Journal of Experimental & Clinical Cancer Research. 2022
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis . Molecular Cell . 2022
Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer . Redox Biology . 2022
Role of lncSLCO1C1 in gastric cancer progression and resistance to oxaliplatin therapy . Clinical and Translational Medicine . 2022
GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma . Journal of Advanced Research . 2022
Hypoxia-induced lncHILAR promotes renal cancer cell invasion and metastasis via ceRNA for the miR-613/206/1-1-3p/Jagged-1/Notch/CXCR4 signaling pathway . Molecular Therapy . 2021
Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy . Cell Death & Differentiation . 2021
CircPDIA3/miR-449a/XBP1 feedback loop curbs pyroptosis by inhibiting palmitoylation of the GSDME-C domain to induce chemoresistance of colorectal cancer. Drug Resistance Updates. 2024 NEW!
Droplets Cas13a-RPA measurement delineates potential role for plasma circWDR37 in colorectal cancer. Aggregate. 2024 NEW!
circMIRIAF aggravates myocardial ischemia-reperfusion injury via targeting miR-544/WDR12 axis. Redox Biology. 2024 NEW!
circFAM193B interaction with PRMT6 regulates AML leukemia stem cells chemoresistance through altering the oxidative metabolism and lipid peroxidation. Leukemia. 2024 NEW!
CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated deubiquitination of PIK3IP1. Journal of Experimental & Clinical Cancer Research. 2024 NEW!
A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity. Journal of Experimental & Clinical Cancer Research. 2024 NEW!
Circular RNA circTATDN3 promotes the Warburg effect and proliferation in colorectal cancer. Lin J, et al. Cancer Letters. 2024 NEW!
Role of circPSEN1 in carbon black and cadmium co-exposure induced autophagy-dependent ferroptosis in respiratory epithelial cells. Mao R, et al. Environmental Pollution. 2024 NEW!
N6-methyladenosine-modified circ_104797 sustains cisplatin resistance in bladder cancer through acting as RNA sponges. Xu C, et al. Cellular & Molecular Biology Letters. 2024 NEW!
A novel circular RNA, circSQSTM1, protects the endothelial function in atherosclerosis. Chen Z, et al. Free Radical Biology & Medicine. 2024 NEW!
Exosome-transported circ_0061407 and circ_0008103 play a tumor-repressive role and show diagnostic value in non-small-cell lung cancer. Chen Z, et al. Journal of Translational Medicine. 2024 NEW!
Exosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction. Gan W, et al. Journal of Translational Medicine. 2024 NEW!
Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. Chen J, et al. Journal of Translational Medicine. 2024 NEW!
Mechanistic insights into aniline-induced liver injury: Role of the mmu_circ_26984/Myh9/NLRP3 axis and modulation by N-acetylcysteine. Fu X, et al. Ecotoxicology and Environmental Safety. 2024 NEW!
Circ_0006949 as a potential non-invasive diagnosis biomarker promotes the proliferation of NSCLC cells via miR-4673/GLUL axis. Bai C, et al. Biochimica et Biophysica Acta. Molecular Basis of Disease. 2024 NEW!
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH. Xie L, et al. Cell Death Discovery. 2024 NEW!
Circular RNA cVIM promotes hepatic stellate cell activation in liver fibrosis via miR-122-5p/miR-9-5p-mediated TGF-β signaling cascade. Zhou Z, et al. Communications Biology. 2024 NEW!
CircUBA2 promotes the cancer stem cell-like properties of gastric cancer through upregulating STC1 via sponging miR-144-5p. Wang J, et al. Cancer Cell International. 2024 NEW!
CircNOLC1 Promotes Colorectal Cancer Liver Metastasis by Interacting with AZGP1 and Sponging miR-212-5p to Regulate Reprogramming of the Oxidative Pentose Phosphate Pathway. Advanced Science. 2023
Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. Journal of Translational Medicine. 2024
CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation. Journal of Experimental & Clinical Cancer Research. 2023
TGF-β signaling promotes cervical cancer metastasis via CDR1as. Molecular Cancer. 2023
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes. Signal Transduction and Targeted Therapy. 2023
CircOGDH Is a Penumbra Biomarker and Therapeutic Target in Acute Ischemic Stroke. Circulation Research. 2022
Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway. Journal of Experimental & Clinical Cancer Research. 2023
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer. Cancer Communications. 2022
CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma. Molecular Cancer. 2022 NEW!
circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA. Journal of Experimental & Clinical Cancer Research. 2022
The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway . Molecular Cancer . 2022
Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p . Molecular Cancer . 2022
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC . Molecular cancer . 2021
CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity . Molecular cancer . 2021;
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output . Cell . 2020;
Extracellular Vesicle-Mediated Delivery of CircSCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models . Circulation . 2020
A Noncoding Regulatory RNAs Network Driven by Circ‐CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma . Hepatology . 2020
o8G Site-Specifically Modified tRF-1-AspGTC: A Novel Therapeutic Target and Biomarker for Pulmonary Hypertension. Circulation Research. 2024 NEW!
Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification. Nature Communications. 2024 NEW!
Targeting SOX13 inhibits assembly of respiratory chain supercomplexes to overcome ferroptosis resistance in gastric cancer. Nature Communications. 2024 NEW!
The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4. Advanced Science. 2024 NEW!
METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs. International Journal of Oral Science. 2024 NEW!
A Novel tsRNA, m7G-3′ tiRNA Lys TTT, Promotes Bladder Cancer Malignancy Via Regulating ANXA2 Phosphorylation. Advanced Science. 2024 NEW!
METTL3-mediated pre-miR-665/DLX3 m6A methylation facilitates the committed differentiation of stem cells from apical papilla. Experimental & Molecular Medicine. 2024 NEW!
m7G-modified mt-tRF3b-LeuTAA regulates mitophagy and metabolic reprogramming via SUMOylation of SIRT3 in chondrocytes. Biomaterials. 2024 NEW!
Adolescent co-exposure to environmental cadmium and high-fat diet induces cognitive decline via Larp7 m6A-mediated SIRT6 inhibition. Journal of Hazardous Materials. 2024 NEW!
WTAP/YTHDF1-mediated m6A modification amplifies IFN-γ-induced immunosuppressive properties of human MSCs. Journal of Advanced Research. 2024 NEW!
tsRNA-GlyGCC promotes colorectal cancer progression and 5-FU resistance by regulating SPIB. Journal of Experimental & Clinical Cancer Research. 2024 NEW!
m6A modification of lncRNA PHKA1-AS1 enhances Actinin Alpha 4 stability and promotes non-small cell lung cancer metastasis. MedComm. 2024 NEW!
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth. Cancer Letters. 2024 NEW!
CircUGGT2 downregulation by METTL14-dependent m6A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR 186-3p/MAP3K9 axis. Pharmacological Research. 2024 NEW!
N6 methyladenosine modified SRPK1 promotes aerobic glycolysis of lung adenocarcinoma via PKM splicing. Cellular & Molecular Biology Letters. 2024 NEW!
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12. Cell Death & Disease. 2024 NEW!
METTL4 mediated-N6-methyladenosine promotes acute lung injury by activating ferroptosis in alveolar epithelial cells. Free Radical Biology and Medicine. 2024 NEW!
Mettl1 knockdown alleviates cardiac I/R injury in mice by inactivating the Mettl1-CYLD-P53 positive feedback loop. Acta Pharmacologica Sinica. 2024 NEW!
Sirt1 m6A modification-evoked Leydig cell senescence promotes Cd-induced testosterone decline. Ecotoxicology and Environmental Safety. 2024 NEW!
m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA. Cell & Bioscience. 2024 NEW!
M6A RNA methylation-mediated TUG1 stability maintains mitochondrial homeostasis during kidney aging by epigenetically regulating PGC1-α expression. Antioxidants & Redox Signaling. 2024 NEW!
TRMT10C-mediated m7G modification of circFAM126A inhibits lung cancer growth by regulating cellular glycolysis. Cell Biology and Toxicology. 2024 NEW!
Dysregulation of pseudouridylation in small RNAs contributes to papillary thyroid carcinoma metastasis. Cancer Cell International. 2024 NEW!
RNA N6-methyladenosine modificationbased biomarkers for absorbed ionizing radiation dose estimation. Nature Communications. 2023
Sperm Rhoa m6A modification mediates intergenerational transmission of paternally acquired hippocampal neuronal senescence and cognitive deficits after combined exposure to environmental cadmium and high-fat diet in mice. Journal of Hazardous Materials. 2023
Specific RNA m6A modification sites in bone marrow mesenchymal stem cells from the jawbone marrow of type 2 diabetes patients with dental implant failure. International Journal of Oral Science. 2023
N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration. Cell Death & Differentiation. 2023
Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7. Molecular Cancer. 2023
Therapeutic m6 A Eraser ALKBH5 mRNALoaded Exosome−Liposome Hybrid Nanoparticles Inhibit Progression of Colorectal Cancer in Preclinical Tumor Models. ACS nano. 2023
KIAA1429 promotes tumorigenesis and gefitinib resistance in lung adenocarcinoma by activating the JNK/ MAPK pathway in an m6A-dependent manner. Drug Resistance Updates. 2023
Specific RNA m6A modification sites in bone marrow mesenchymal stem cells from the jawbone marrow of type 2 diabetes patients with dental implant failure. International Journal of Oral Science. 2023
KIAA1429 promotes tumorigenesis and gefitinib resistance in lung adenocarcinoma by activating the JNK/ MAPK pathway in an m6A-dependent manner. Drug Resistance Updates. 2023
Therapeutic m6 A Eraser ALKBH5 mRNA[1]Loaded Exosome−Liposome Hybrid Nanoparticles Inhibit Progression of Colorectal Cancer in Preclinical Tumor Models. ACS nano. 2023
FTO-dependent m6 A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke. Nature Communications. 2023
Sperm Rhoa m6A modification mediates intergenerational transmission of paternally acquired hippocampal neuronal senescence and cognitive deficits after combined exposure to environmental cadmium and high-fat diet in mice. Journal of Hazardous Materials. 2023
N6 -methyladenosine plays a dual role in arsenic carcinogenesis by temporal-specific control of core target AKT1. Journal of Hazardous Materials. 2022
PGE2‐EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase. The EMBO Journal. 2022
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , Molecular Cancer . 2022
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer . Molecular Cancer . 2022
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis . Cell Death & Differentiation . 2022
METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis . Journal of Experimental & Clinical Cancer Research . 2022
m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels . Cancer Communications . 2022
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression . Oncogene . 2022
The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis . American Journal of Respiratory Cell and Molecular Biology . 2022
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1 . Theranostics . 2021
ALKBH5-mediated m6A mRNA Methylation Governs Human Embryonic Stem Cell Cardiac Commitment . Molecular Therapy-Nucleic Acids . 2021
ALKBH5 suppresses tumor progression via an m 6 A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma . Cell Death & Disease . 2021
N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1-Regulated Astrocyte Dysfunction and Depressive-like Behaviors. . Biological Paychiatry . 2020
SIRT1 regulates N6‐methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2‐dependent FTO SUMOylation . Hepatology . 2020
P1.02D.02 Tumor-Derived Exosomal tsRNA 3’ tiRNA-AlaCGC Promotes Immune Tolerance by Inducing Fibroblast Senescence in LUAD. Journal of Thoracic Oncology. 2024 NEW!
Faecal hsa-miR-7704 inhibits the growth and adhesion of Bifidobacterium longum by suppressing ProB and aggravates hepatic encephalopathy. npj Biofilms and Microbiomes. 2024 NEW!
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component. Environmental Pollution. 2024 NEW!
PTransfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of bromodulin. Cellular & Molecular Biology Letters. 2024 NEW!
Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of bromodulin. Cellular & Molecular Biology Letters. 2024 NEW!
Xuefu Zhuyu Decoction promotes synaptic plasticity by targeting miR-191a-5p/BDNF-TrkB axis in severe traumatic brain injury. Phytomedicine. 2024 NEW!
U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression. Breast Cancer Research. 2024 NEW!
PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer. Cell Death Discovery. 2024 NEW!
Exosomes from umbilical cord mesenchymal stem cells ameliorate intervertebral disc degeneration via repairing mitochondrial dysfunction. Journal of Orthopaedic Translation. 2024 NEW!
Downregulation of tRF-Cys-GCA-029 by hyperglycemia promotes tumorigenesis and glycolysis of diabetic breast cancer through upregulating PRKCG translation. Breast Cancer Research. 2024 NEW!
Optimizing of a suitable protocol for isolating tissue-derived extracellular vesicles and profiling small RNA patterns in hepatocellular carcinoma. Liver International. 2024 NEW!
Optimizing of a suitable protocol for isolating tissue-derived extracellular vesicles and profiling small RNA patterns in hepatocellular carcinoma. Liver International. 2024 NEW!
miR-99b-3p/Mmp13 axis regulates NLRP3 inflammasome-dependent microglial pyroptosis and alleviates neuropathic pain via the promotion of autophagy. International Immunopharmacology. 2024 NEW!
tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. Signal Transduction and Targeted Therapy. 2023
Cell-Free Osteoarthritis Treatment with Sustained-Release of Chondrocyte-Targeting Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells to Rejuvenate Aging Chondrocytes. ACS nano. 2023
piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination. Experimental & Molecular Medicine. 2023
PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer. Cell Death Discovery. 2024
A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes . Journal of hematology & oncology . 2022
A novel 3’tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer . Cell Death & Disease . 2022
tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner . Journal of Experimental & Clinical Cancer Research . 2022
Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis . Cell Death & Disease . 2022
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex . Cell Reports . 2022
TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis . iScience . 2022
Maternal genetic effect on apoptosis of ovarian granulosa cells induced by cadmium. Food and Chemical Toxicology .2022
Cadmium disrupts mouse embryonic stem cell differentiation into ovarian granulosa cells through epigenetic mechanisms . Ecotoxicology and Environmental Safety . 2022
miR-6769b-5p targets CCND-1 to regulate proliferation in cadmium-treated placental trophoblasts: Association with the impairment of fetal growth . Ecotoxicology and Environmental Safety . 2022
Identification of Small Nucleolar RNA SNORD60 as a Potential Biomarker and Its Clinical Significance in Lung Adenocarcinoma . BioMed Research International . 2022
A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer . Molecular cancer . 2021
Altered sperm tsRNAs in aged male contribute to anxiety‐like behavior in offspring . Aging Cell . 2021
A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer . Journal of Experimental & Clinical Cancer Research . 2021
Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells . PLoS genetics . 2021
Glioma glycolipid metabolism: MSI2–SNORD12B–FIP1L1–ZBTB4 feedback loop as a potential treatment target . Clinical and translational medicine . 2021
Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src . Signal transduction and targeted therapy . 2021
Diverging targets mediate the pathological role of miR-199a-5p and miR-199-3p by promoting cardiac hypertrophy and fibrosis . Molecular Therapy-Nucleic Acids . 2021
Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis . Journal of Experimental & Clinical Cancer Research . 2021
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone . Molecular Medicine . 2021
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling . Inflammatory Bowel Diseases . 2021
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance . Theranostics . 2020
Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer . Cell Death & Disease . 2020
Activation of AMPK inhibits cervical cancer growth by hyperacetylation of H3K9 through PCAF. Cell Communication and Signaling. 2024 NEW!
OsBBP1, a newly identified protein containing DUF630 and DUF632 domains confers drought tolerance in rice. Plant Science. 2024 NEW!
5-Aza-2-Deoxycytidine Ameliorates Choroidal Neovascularization by Inhibiting the Wnt/β-Catenin Signaling Pathway. Investigative Ophthalmology & Visual Science. 2024 NEW!
Role of Integrin β1 and Tenascin C Mediate TGF-SMAD2/3 Signaling in Chondrogenic Differentiation of BMSCs Induced by Type I Collagen Hydrogel. Regenerative Biomaterials. 2024 NEW!
A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy, Cell Death & Differentiation. 2023
TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1. Experimental & Molecular Medicine. 2023
Maternal inulin alleviates high-fat diet-induced lipid disorder in offspring by epigenetically modulating hypothalamus feeding circuit-related genes. Food & Function. 2023
DNA hydroxymethylation reprogramming of β-oxidation genes mediates early-life arsenic-evoked hepatic lipid accumulation in adult mice. Journal of Hazardous Materials . 2022
Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription. Journal of Hepatology . 2021
Oncogenic role of SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2 positive diffuse large B-cell lymphomas. Blood . 2021
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain. Nature communications . 2021
Histone demethylase KDM6A promotes somatic cell reprogramming by epigenetically regulating the PTEN and IL‐6 signal pathways . STEM CELLS . 2020
Multi-generational obesogenic effects of sulfomethoxazole on Caenorhabditis elegans through epigenetic regulation . Journal of Hazardous Materials . 2019
Targeting SOX13 inhibits assembly of respiratory chain supercomplexes to overcome ferroptosis resistance in gastric cancer. Nature Communications. 2024 NEW!
A Novel tsRNA, m7G-3′ tiRNA Lys TTT, Promotes Bladder Cancer Malignancy Via Regulating ANXA2 Phosphorylation. Advanced Science. 2024 NEW!
METTL4 mediated-N6-methyladenosine promotes acute lung injury by activating ferroptosis in alveolar epithelial cells. Free Radical Biology and Medicine. 2024 NEW!
Metabolomics integrated with network pharmacology of blood-entry constituents reveals the bioactive component of Xuefu Zhuyu decoction and its angiogenic effects in treating traumatic brain injury. Chinese Medicine. 2024 NEW!
Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors. Cell Reports Medicine. 2023
tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. Signal Transduction and Targeted Therapy. 2023
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes. Signal Transduction and Targeted Therapy. 2023
Long non-coding RNA DDX11-AS1 promotes the proliferation and migration of glioma cells by combining with HNRNPC . Molecular Therapy-Nucleic Acids . 2022
Trehalose Protects Keratinocytes against Ultraviolet B Radiation by Activating Autophagy via Regulating TIMP3 and ATG9A . Oxidative Medicine and Cellular Longevity . 2022
2, 3, 5, 4’-tetrahydroxy-stilbene-2-O-β-D-glucoside ameliorates NAFLD via attenuating hepatic steatosis through inhibiting mitochondrial dysfunction dependent on SIRT5 . Phytomedicine . 2022
Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription . Journal of Hepatology . 2021
Antihypertrophic Memory after Regression of Exercise-induced Physiological Myocardial Hypertrophy is Mediated by the Long Noncoding RNA Mhrt779 . Circulation . 2021
N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression . Molecular cell . 2021
Nidogen1-enriched extracellular vesicles accelerate angiogenesis and bone regeneration by targeting Myosin-10 to regulate endothelial cell adhesion . Bioactive Materials . 2021
A tumor-suppressive circular RNA mediates uncanonical integrin degradation by the proteasome in liver cancer . Science Advances . 2021
Glioblastoma cell–derived lncRNA-containing exosomes induce microglia to produce complement C5, promoting chemotherapy resistance . Cancer immunology research . 2021
Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis . Nature communications . 2019
Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13. 32 accelerates tumorigenesis . Nucleic acids research . 2019
Aberrant R-loop–mediated immune evasion, cellular communication, and metabolic reprogramming afect cancer progression: a single-cell analysis. Molecular Cancer. 2024 NEW!
Dysregulation of R-loop homeostasis shapes the immunosuppressive microenvironment and induces malignant progression in melanoma. Apoptosis. 2024 NEW!
Small Molecule Hydrogels Loading Small Molecule Drugs from Chinese Medicine for the Enhanced Treatment of Traumatic Brain Injury. ACS Nano. 2024 NEW!
α-parvin controls chondrocyte column formation and regulates long bone development. Bone Research. 2023 NEW!
N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to
promote heart regeneration. Nature Communications. 2024 NEW!
Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors. Cell Reports Medicine. 2024 NEW!
N6-methyladenosine-mediated upregulation of LNCAROD confers radioresistance in esophageal squamous cell carcinoma through stabilizing PARP. Clinical And Translational Medicine. 2024 NEW!
HIF-1 induced tiRNA-Lys-CTT-003 is protective against cisplatin induced ferroptosis of renal tubular cells in mouse AKI model. Biochimica Et Biophysica Acta: Molecular Basis Of Disease. 2024 NEW!
Protein interactome analysis of ATP1B1 in alveolar epithelial cells using Co-Immunoprecipitation mass spectrometry and parallel reaction monitoring assay. Heliyon. 2024 NEW!
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes. Signal Transduction and Targeted Therapy. 2023
LINC01615 maintains cell survival in adaptation to nutrient starvation through the pentose phosphate pathway and modulates chemosensitivity in colorectal cancer. Cellular and Molecular Life Sciences. 2023
Enterovirus A71 Promotes Exosome Secretion by the Nonstructural Protein 3A Interacting with Rab27a. Microbiology Spectrum. 2023
Long non-coding RNA DDX11-AS1 promotes the proliferation and migration of glioma cells by combining with HNRNPC. Molecular Therapy-Nucleic Acids. 2022
Novel lncRNA-prader willi/angelman region RNA, SNRPN neighbour (PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease. Cell Proliferation. 2022
Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription. Journal of Hepatology. 2021
Antihypertrophic Memory after Regression of Exercise-induced Physiological Myocardial Hypertrophy is Mediated by the Long Noncoding RNA Mhrt779. Circulation. 2021
Glioblastoma cell–derived lncRNA-containing exosomes induce microglia to produce complement C5, promoting chemotherapy resistance. Cancer Immunology Research. 2021
Long noncoding RNA LYPLAL1-AS1 regulates adipogenic differentiation of human mesenchymal stem cells by targeting desmoplakin and inhibiting the Wnt/β-catenin pathway. Cell Death Discovery. 2021
LncRNA H19 downregulation confers erlotinib resistance through upregulation of PKM2 and phosphorylation of AKT in EGFR-mutant lung cancers. Cancer Letters. 2020
