LncRNA PSMB8-AS1 Instigates Vascular Inflammation to Aggravate Atherosclerosis. Circulation Research. 2023 NEW!
High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA. Signal Transduction and Targeted Therapy. 2023 NEW!
LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer. Journal of Experimental & Clinical Cancer Research. 2024 NEW!
A lncRNA signature associated with tumor immune heterogeneity predicts distant metastasis in locoregionally advanced nasopharyngeal carcinoma. Nature Communications. 2023
FAR591 promotes the pathogenesis and progression of SONFH by regulating Fos expression to mediate the apoptosis of bone microvascular endothelial cells. Bone Research. 2023
LncRNA NIPA1-SO confers atherosclerotic protection by suppressing the transmembrane protein NIPA1. Journal of Advanced Research. 2023
Lnc Tmem235 promotes repair of early steroid-induced osteonecrosis of the femoral head by inhibiting hypoxiainduced apoptosis of BMSCs. Experimental & Molecular Medicine. 2022
Mmu-LncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p /HtrA3 signaling axis. Molecular Therapy. 2022
Acylglycerol kinase promotes ovarian cancer progression and regulates mitochondria function by interacting with ribosomal protein L39. Journal of Experimental & Clinical Cancer Research. 2022
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis . Molecular Cell . 2022
Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer . Redox Biology . 2022
Role of lncSLCO1C1 in gastric cancer progression and resistance to oxaliplatin therapy . Clinical and Translational Medicine . 2022
GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma . Journal of Advanced Research . 2022
Hypoxia-induced lncHILAR promotes renal cancer cell invasion and metastasis via ceRNA for the miR-613/206/1-1-3p/Jagged-1/Notch/CXCR4 signaling pathway . Molecular Therapy . 2021
Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy . Cell Death & Differentiation . 2021
CircNOLC1 Promotes Colorectal Cancer Liver Metastasis by Interacting with AZGP1 and Sponging miR-212-5p to Regulate Reprogramming of the Oxidative Pentose Phosphate Pathway. Advanced Science. 2023 NEW!
Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. Journal of Translational Medicine. 2024 NEW!
CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation. Journal of Experimental & Clinical Cancer Research. 2023 NEW!
TGF-β signaling promotes cervical cancer metastasis via CDR1as. Molecular Cancer. 2023
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes. Signal Transduction and Targeted Therapy. 2023
CircOGDH Is a Penumbra Biomarker and Therapeutic Target in Acute Ischemic Stroke. Circulation Research. 2022
Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway. Journal of Experimental & Clinical Cancer Research. 2023
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer. Cancer Communications. 2022
CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma. Molecular Cancer. 2022 NEW!
circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA. Journal of Experimental & Clinical Cancer Research. 2022
The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway . Molecular Cancer . 2022
Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p . Molecular Cancer . 2022
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC . Molecular cancer . 2021
CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity . Molecular cancer . 2021;
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output . Cell . 2020;
Extracellular Vesicle-Mediated Delivery of CircSCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models . Circulation . 2020
A Noncoding Regulatory RNAs Network Driven by Circ‐CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma . Hepatology . 2020
RNA N6-methyladenosine modificationbased biomarkers for absorbed ionizing radiation dose estimation. Nature Communications. 2023 NEW!
Sperm Rhoa m6A modification mediates intergenerational transmission of paternally acquired hippocampal neuronal senescence and cognitive deficits after combined exposure to environmental cadmium and high-fat diet in mice. Journal of Hazardous Materials. 2023 NEW!
Specific RNA m6A modification sites in bone marrow mesenchymal stem cells from the jawbone marrow of type 2 diabetes patients with dental implant failure. International Journal of Oral Science. 2023 NEW!
N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration. Cell Death & Differentiation. 2023 NEW!
Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7. Molecular Cancer. 2023 NEW!
Therapeutic m6 A Eraser ALKBH5 mRNALoaded Exosome−Liposome Hybrid Nanoparticles Inhibit Progression of Colorectal Cancer in Preclinical Tumor Models. ACS nano. 2023 NEW!
KIAA1429 promotes tumorigenesis and gefitinib resistance in lung adenocarcinoma by activating the JNK/ MAPK pathway in an m6A-dependent manner. Drug Resistance Updates. 2023 NEW!
Specific RNA m6A modification sites in bone marrow mesenchymal stem cells from the jawbone marrow of type 2 diabetes patients with dental implant failure. International Journal of Oral Science. 2023
KIAA1429 promotes tumorigenesis and gefitinib resistance in lung adenocarcinoma by activating the JNK/ MAPK pathway in an m6A-dependent manner. Drug Resistance Updates. 2023
Therapeutic m6 A Eraser ALKBH5 mRNA[1]Loaded Exosome−Liposome Hybrid Nanoparticles Inhibit Progression of Colorectal Cancer in Preclinical Tumor Models. ACS nano. 2023
FTO-dependent m6 A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke. Nature Communications. 2023
Sperm Rhoa m6A modification mediates intergenerational transmission of paternally acquired hippocampal neuronal senescence and cognitive deficits after combined exposure to environmental cadmium and high-fat diet in mice. Journal of Hazardous Materials. 2023
N6 -methyladenosine plays a dual role in arsenic carcinogenesis by temporal-specific control of core target AKT1. Journal of Hazardous Materials. 2022
PGE2‐EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase. The EMBO Journal. 2022
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , Molecular Cancer . 2022
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer . Molecular Cancer . 2022
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis . Cell Death & Differentiation . 2022
METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis . Journal of Experimental & Clinical Cancer Research . 2022
m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels . Cancer Communications . 2022
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression . Oncogene . 2022
The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis . American Journal of Respiratory Cell and Molecular Biology . 2022
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1 . Theranostics . 2021
ALKBH5-mediated m6A mRNA Methylation Governs Human Embryonic Stem Cell Cardiac Commitment . Molecular Therapy-Nucleic Acids . 2021
ALKBH5 suppresses tumor progression via an m 6 A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma . Cell Death & Disease . 2021
N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1-Regulated Astrocyte Dysfunction and Depressive-like Behaviors. . Biological Paychiatry . 2020
SIRT1 regulates N6‐methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2‐dependent FTO SUMOylation . Hepatology . 2020
tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. Signal Transduction and Targeted Therapy. 2023 NEW!
Cell-Free Osteoarthritis Treatment with Sustained-Release of Chondrocyte-Targeting Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells to Rejuvenate Aging Chondrocytes. ACS nano. 2023 NEW!
piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination. Experimental & Molecular Medicine. 2023 NEW!
PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer. Cell Death Discovery. 2024 NEW!
A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes . Journal of hematology & oncology . 2022
A novel 3’tRNA-derived fragment tRF-Val promotes proliferation and inhibits apoptosis by targeting EEF1A1 in gastric cancer . Cell Death & Disease . 2022
tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner . Journal of Experimental & Clinical Cancer Research . 2022
Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis . Cell Death & Disease . 2022
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex . Cell Reports . 2022
TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis . iScience . 2022
Maternal genetic effect on apoptosis of ovarian granulosa cells induced by cadmium. Food and Chemical Toxicology .2022
Cadmium disrupts mouse embryonic stem cell differentiation into ovarian granulosa cells through epigenetic mechanisms . Ecotoxicology and Environmental Safety . 2022
miR-6769b-5p targets CCND-1 to regulate proliferation in cadmium-treated placental trophoblasts: Association with the impairment of fetal growth . Ecotoxicology and Environmental Safety . 2022
Identification of Small Nucleolar RNA SNORD60 as a Potential Biomarker and Its Clinical Significance in Lung Adenocarcinoma . BioMed Research International . 2022
A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer . Molecular cancer . 2021
Altered sperm tsRNAs in aged male contribute to anxiety‐like behavior in offspring . Aging Cell . 2021
A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer . Journal of Experimental & Clinical Cancer Research . 2021
Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells . PLoS genetics . 2021
Glioma glycolipid metabolism: MSI2–SNORD12B–FIP1L1–ZBTB4 feedback loop as a potential treatment target . Clinical and translational medicine . 2021
Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src . Signal transduction and targeted therapy . 2021
Diverging targets mediate the pathological role of miR-199a-5p and miR-199-3p by promoting cardiac hypertrophy and fibrosis . Molecular Therapy-Nucleic Acids . 2021
Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis . Journal of Experimental & Clinical Cancer Research . 2021
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone . Molecular Medicine . 2021
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling . Inflammatory Bowel Diseases . 2021
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance . Theranostics . 2020
Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer . Cell Death & Disease . 2020
A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy, Cell Death & Differentiation. 2023 NEW!
TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1. Experimental & Molecular Medicine. 2023 NEW!
Maternal inulin alleviates high-fat diet-induced lipid disorder in offspring by epigenetically modulating hypothalamus feeding circuit-related genes. Food & Function. 2023 NEW!
DNA hydroxymethylation reprogramming of β-oxidation genes mediates early-life arsenic-evoked hepatic lipid accumulation in adult mice. Journal of Hazardous Materials . 2022
Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription. Journal of Hepatology . 2021
Oncogenic role of SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2 positive diffuse large B-cell lymphomas. Blood . 2021
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain. Nature communications . 2021
Histone demethylase KDM6A promotes somatic cell reprogramming by epigenetically regulating the PTEN and IL‐6 signal pathways . STEM CELLS . 2020
Multi-generational obesogenic effects of sulfomethoxazole on Caenorhabditis elegans through epigenetic regulation . Journal of Hazardous Materials . 2019
Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors. Cell Reports Medicine. 2023 NEW!
tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. Signal Transduction and Targeted Therapy. 2023 NEW!
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes. Signal Transduction and Targeted Therapy. 2023 NEW!
Long non-coding RNA DDX11-AS1 promotes the proliferation and migration of glioma cells by combining with HNRNPC . Molecular Therapy-Nucleic Acids . 2022
Trehalose Protects Keratinocytes against Ultraviolet B Radiation by Activating Autophagy via Regulating TIMP3 and ATG9A . Oxidative Medicine and Cellular Longevity . 2022
2, 3, 5, 4’-tetrahydroxy-stilbene-2-O-β-D-glucoside ameliorates NAFLD via attenuating hepatic steatosis through inhibiting mitochondrial dysfunction dependent on SIRT5 . Phytomedicine . 2022
Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription . Journal of Hepatology . 2021
Antihypertrophic Memory after Regression of Exercise-induced Physiological Myocardial Hypertrophy is Mediated by the Long Noncoding RNA Mhrt779 . Circulation . 2021
N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression . Molecular cell . 2021
Nidogen1-enriched extracellular vesicles accelerate angiogenesis and bone regeneration by targeting Myosin-10 to regulate endothelial cell adhesion . Bioactive Materials . 2021
A tumor-suppressive circular RNA mediates uncanonical integrin degradation by the proteasome in liver cancer . Science Advances . 2021
Glioblastoma cell–derived lncRNA-containing exosomes induce microglia to produce complement C5, promoting chemotherapy resistance . Cancer immunology research . 2021
Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis . Nature communications . 2019
Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13. 32 accelerates tumorigenesis . Nucleic acids research . 2019
