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单细胞测序技术服务 靶向单细胞测序（lncRNA&mRNA） 单细胞测序 |
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生物分子凝聚体研究 HyPro靶RNA临近标记技术 |
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NGS测序技术服务 R-loop 测序（DRIPc-seq） |
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NGS测序技术服务 环状DNA测序（eccDNA测序） |
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Ribo-seq Ribo seq（ribosome profiling） |
核糖体-新生肽链复合物(RNC) RNC联合 circRNA芯片 RNC联合 lncRNA芯片 RNC-seq |
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蛋白表达定量 Label free非标定量 TMT标记定量 PRM靶向定量 |
o8G Site-Specifically Modified tRF-1-AspGTC: A Novel Therapeutic Target and Biomarker for Pulmonary Hypertension. Circulation Research. 2024
Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification. Nature Communications. 2024
Targeting SOX13 inhibits assembly of respiratory chain supercomplexes to overcome ferroptosis resistance in gastric cancer. Nature Communications. 2024
The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4. Advanced Science. 2024
METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs. International Journal of Oral Science. 2024
A Novel tsRNA, m7G-3′ tiRNA Lys TTT, Promotes Bladder Cancer Malignancy Via Regulating ANXA2 Phosphorylation. Advanced Science. 2024
METTL3-mediated pre-miR-665/DLX3 m6A methylation facilitates the committed differentiation of stem cells from apical papilla. Experimental & Molecular Medicine. 2024
m7G-modified mt-tRF3b-LeuTAA regulates mitophagy and metabolic reprogramming via SUMOylation of SIRT3 in chondrocytes. Biomaterials. 2024
Adolescent co-exposure to environmental cadmium and high-fat diet induces cognitive decline via Larp7 m6A-mediated SIRT6 inhibition. Journal of Hazardous Materials. 2024
WTAP/YTHDF1-mediated m6A modification amplifies IFN-γ-induced immunosuppressive properties of human MSCs. Journal of Advanced Research. 2024
tsRNA-GlyGCC promotes colorectal cancer progression and 5-FU resistance by regulating SPIB. Journal of Experimental & Clinical Cancer Research. 2024
m6A modification of lncRNA PHKA1-AS1 enhances Actinin Alpha 4 stability and promotes non-small cell lung cancer metastasis. MedComm. 2024
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth. Cancer Letters. 2024
CircUGGT2 downregulation by METTL14-dependent m6A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR 186-3p/MAP3K9 axis. Pharmacological Research. 2024
N6 methyladenosine modified SRPK1 promotes aerobic glycolysis of lung adenocarcinoma via PKM splicing. Cellular & Molecular Biology Letters. 2024
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12. Cell Death & Disease. 2024
METTL4 mediated-N6-methyladenosine promotes acute lung injury by activating ferroptosis in alveolar epithelial cells. Free Radical Biology and Medicine. 2024
Mettl1 knockdown alleviates cardiac I/R injury in mice by inactivating the Mettl1-CYLD-P53 positive feedback loop. Acta Pharmacologica Sinica. 2024
Sirt1 m6A modification-evoked Leydig cell senescence promotes Cd-induced testosterone decline. Ecotoxicology and Environmental Safety. 2024
m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA. Cell & Bioscience. 2024
M6A RNA methylation-mediated TUG1 stability maintains mitochondrial homeostasis during kidney aging by epigenetically regulating PGC1-α expression. Antioxidants & Redox Signaling. 2024
TRMT10C-mediated m7G modification of circFAM126A inhibits lung cancer growth by regulating cellular glycolysis. Cell Biology and Toxicology. 2024
Dysregulation of pseudouridylation in small RNAs contributes to papillary thyroid carcinoma metastasis. Cancer Cell International. 2024
