CircPDIA3/miR-449a/XBP1 feedback loop curbs pyroptosis by inhibiting palmitoylation of the GSDME-C domain to induce chemoresistance of colorectal cancer. Drug Resistance Updates. 2024 NEW!
Droplets Cas13a-RPA measurement delineates potential role for plasma circWDR37 in colorectal cancer. Aggregate. 2024 NEW!
circMIRIAF aggravates myocardial ischemia-reperfusion injury via targeting miR-544/WDR12 axis. Redox Biology. 2024 NEW!
circFAM193B interaction with PRMT6 regulates AML leukemia stem cells chemoresistance through altering the oxidative metabolism and lipid peroxidation. Leukemia. 2024 NEW!
CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated deubiquitination of PIK3IP1. Journal of Experimental & Clinical Cancer Research. 2024 NEW!
A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity. Journal of Experimental & Clinical Cancer Research. 2024 NEW!
Circular RNA circTATDN3 promotes the Warburg effect and proliferation in colorectal cancer. Lin J, et al. Cancer Letters. 2024 NEW!
Role of circPSEN1 in carbon black and cadmium co-exposure induced autophagy-dependent ferroptosis in respiratory epithelial cells. Mao R, et al. Environmental Pollution. 2024 NEW!
N6-methyladenosine-modified circ_104797 sustains cisplatin resistance in bladder cancer through acting as RNA sponges. Xu C, et al. Cellular & Molecular Biology Letters. 2024 NEW!
A novel circular RNA, circSQSTM1, protects the endothelial function in atherosclerosis. Chen Z, et al. Free Radical Biology & Medicine. 2024 NEW!
Exosome-transported circ_0061407 and circ_0008103 play a tumor-repressive role and show diagnostic value in non-small-cell lung cancer. Chen Z, et al. Journal of Translational Medicine. 2024 NEW!
Exosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction. Gan W, et al. Journal of Translational Medicine. 2024 NEW!
Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. Chen J, et al. Journal of Translational Medicine. 2024 NEW!
Mechanistic insights into aniline-induced liver injury: Role of the mmu_circ_26984/Myh9/NLRP3 axis and modulation by N-acetylcysteine. Fu X, et al. Ecotoxicology and Environmental Safety. 2024 NEW!
Circ_0006949 as a potential non-invasive diagnosis biomarker promotes the proliferation of NSCLC cells via miR-4673/GLUL axis. Bai C, et al. Biochimica et Biophysica Acta. Molecular Basis of Disease. 2024 NEW!
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH. Xie L, et al. Cell Death Discovery. 2024 NEW!
Circular RNA cVIM promotes hepatic stellate cell activation in liver fibrosis via miR-122-5p/miR-9-5p-mediated TGF-β signaling cascade. Zhou Z, et al. Communications Biology. 2024 NEW!
CircUBA2 promotes the cancer stem cell-like properties of gastric cancer through upregulating STC1 via sponging miR-144-5p. Wang J, et al. Cancer Cell International. 2024 NEW!
CircNOLC1 Promotes Colorectal Cancer Liver Metastasis by Interacting with AZGP1 and Sponging miR-212-5p to Regulate Reprogramming of the Oxidative Pentose Phosphate Pathway. Advanced Science. 2023
Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. Journal of Translational Medicine. 2024
CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation. Journal of Experimental & Clinical Cancer Research. 2023
TGF-β signaling promotes cervical cancer metastasis via CDR1as. Molecular Cancer. 2023
CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes. Signal Transduction and Targeted Therapy. 2023
CircOGDH Is a Penumbra Biomarker and Therapeutic Target in Acute Ischemic Stroke. Circulation Research. 2022
Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway. Journal of Experimental & Clinical Cancer Research. 2023
EIF4a3-regulated circRABL2B regulates cell stemness and drug sensitivity of lung cancer via YBX1-dependent downregulation of MUC5AC expression. International Journal of Biological Sciences. 2023
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer. Cancer Communications. 2022
CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma. Molecular Cancer. 2022
circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA. Journal of Experimental & Clinical Cancer Research. 2022
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway. International Journal of Biological Sciences. 2022
The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway . Molecular Cancer . 2022
Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p . Molecular Cancer . 2022
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC . Molecular cancer . 2021
CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity . Molecular cancer . 2021
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output . Cell . 2020
Extracellular Vesicle-Mediated Delivery of CircSCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models . Circulation . 2020
A Noncoding Regulatory RNAs Network Driven by Circ‐CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma . Hepatology . 2020
N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis . Nature Communications . 2020
CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer . Molecular Cancer . 2020
Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals . Molecular cancer . 2020
circGSK3β promotes metastasis in esophageal squamous cell carcinoma by augmenting β-catenin signaling . Molecular cancer . 2020
circKIF4A acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancer . Molecular Cancer . 2020
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion . Immunity . 2018
Circular RNA MTO1 acts as the sponge of miR-9 to suppress hepatocellular carcinoma progression . Hepatology (Baltimore, Md.) . 2017
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC . Molecular cancer . 2021
27.287CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity . Molecular cancer . 2021
27.287PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition . Clinical Cancer Research . 2018
circRNA Mediates Silica-Induced Macrophage Activation Via HECTD1/ZC3H12A-Dependent Ubiquitination . Theranostics . 2017
A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair . Theranostics . 2017
The circular RNA circPRKCI promotes tumor growth in lung adenocarcinoma . Cancer Research . 2018
circEPSTI1 as a prognostic marker and mediator of triple-negative breast cancer progression . Theranostics . 2018
Enhanced breast cancer progression by mutant p53 is inhibited by the circular RNA circ-Ccnb1 . Cell Death & Differentiation . 2018
The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/FAM65B pathway . Cell Death & Differentiation . 2018
A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling . Molecular Cancer . 2019
circKIF4A acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancer . Molecular Cancer . 2019
Circular RNA cTFRC acts as the sponge of MicroRNA-107 to promote bladder carcinoma progression . Molecular Cancer . 2019
Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by controlling TIF1γ in non-small cell lung cancer . Molecular cancer . 2018
Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway . Oncogene . 2018
Tumor-released exosomal circular RNA PDE8A promotes invasive growth via the miR-338/MACC1/MET pathway in pancreatic cancer . Cancer letters . 2018
CircIRAK3 sponges miR-3607 to facilitate breast cancer metastasis . Cancer Letters . 2018
Tumor-released exosomal circular RNA PDE8A promotes invasive growth via the miR-338/MACC1/MET pathway in pancreatic cancer . Cancer letters . 2018
Silencing circular RNA hsa_circ_0000977 suppresses pancreatic ductal adenocarcinoma progression by stimulating miR-874-3p and inhibiting PLK1 expression . Cancer Letters . 2018
CircSETD3 (Hsa_circ_0000567) acts as a sponge for microRNA-421 inhibiting hepatocellular carcinoma growth . Journal of Experimental & Clinical Cancer Research . 2019
Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis . Journal of Experimental & Clinical Cancer Research . 2018
circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346 . Journal of Experimental & Clinical Cancer Research . 2018
Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression . Molecular Cancer . 2017
MicroRNA-1224 splicing circularRNA-Filip1l in an Ago2-dependent manner regulates chronic inflammatory pain via targeting Ubr5 . Journal of Neuroscience . 2019
