2025年SCI成果

2025年SCI成果

tRF3a-MetCAT promotes EGFR-targeted therapeutic resistance through the TRIM21 STAT1-C5a axis in lung adenocarcinoma. Research. 2025

WDR5-H3K4me3 Epigenetic Axis Promotes TRMT6-Dependent tRNA M1A Modification to Facilitate Triple-Negative Breast Cancer Progression by Suppressing Ferroptosis. Advanced Science. 2025

tRNA-derived fragment tRF-24 drives CELF1 phase separation to promote oncogenic splicing in esophageal squamous cell carcinoma. J Exp Clin Cancer Res. 2025

tRNA-Derived Fragment tRF-22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitinationin Esophageal Squamous Cell Carcinoma. Advanced Science. 2025

Icariin-loaded GelMa hydrogel encapsulated potassium sodium niobate biomimetic piezoelectric scaffold regulates macrophage polarization to accelerate bone defect repair. Materials Today Bio. 2025

TRMT6-mediated tRNA m1A modification acts as a translational checkpoint of histone synthesis and facilitates colorectal cancer progression. Nature Cancer. 2025

Profiling fear-extinction learning induced small ncRNAs landscape and identifying miR 29b-3p as a promising biomarker for PTSD. J Transl Med. 2025

Tumor-derived exosomal tsRNA 3′tiRNA-AlaCGC in promoting f ibroblast senescence and Galectin-9 secretion to induce immune tolerance in lung adenocarcinoma. Cell Death Discovery. 2025

Plasma exosomal tsRNA may be used as a marker for differential diagnosis of benign and malignant pulmonary nodules. Journal of Translational Medicine. 2025

tRF16 affects NFKBIA stability and promotes osteoarthritis progression by regulating ALKBH5 expression in m6A-dependent manner.Communications Biology. 2025

tRF(Ala-AGC-3-M8) attenuates neuroinflammation and neuronal damage in Alzheimer’s disease via the EphA7-ERK1/2-p70S6K signaling pathway. Alzheimers Research & Therapy. 2025

tiRNA-HAR contributes to ischemic myocardial injury via facilitating HuR-mediated stability of P53. Translational Research. 2025

tRF-5028c disrupts trophoblast function in recurrent spontaneous abortion by inhibiting CRKL-mediated Rap1 signaling pathway. Cellular & Molecular Biology Letters. 2025

TRMT10A regulates tRNA-ArgCCT m1G9 modification to generate tRNA-derived fragments influencing vasculogenic mimicry formation in glioblastoma. Cell Death & Disease. 2025

Identification of serum tRNA-derived small RNAs biosignature for diagnosis of tuberculosis. Emerging Microbes & Infections. 2025

sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2. Cell Communication and Signaling. 2025

SNORA47 affects stemness and chemotherapy sensitivity via EBF3/RPL11/c-Myc axis in luminal A breast cancer . Molecular Medicine. 2025

piR-hsa-35410 promotes triple-negative breast cancer progression via enhancing PFKL mediated glycolysis. Biochemical Pharmacology. 2025

Mixed lymphocyte reaction-conditioned MSC-derived extracellular vesicles enhance graft survival via miR-638-mediated immunoregulation. Stem Cells Translational Medicine. 2025

The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation. ImmunoTargets and Therapy. 2025

PIWI‐interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation. Clinical And Translational Medicine. 2025

circSP199a, a circularized RNA sponge targeting miR-199a-5p and-3p, mitigates mouse cardiac hypertrophy and fibrosis. Acta Pharmacologica Sinica. 2025

tRNA-Derived Small RNA Accelerates Tumorigenesis through Crosstalk with Tumor-Associated Macrophages, and Downregulation with Cell Membrane-Modified Polymer Nanoparticles Enables Treatment Response. Acs Applied Materials & Interfaces. 2025

SNORA58 Facilitates Radioresistance via Suppressing JNK1-Mediated Ferroptosis in Esophageal Squamous Cell Carcinoma. Advanced Science. 2025