01已发表的研究（231 篇）
这份清单收录的是使用数谱生物 RNA 修饰相关服务与产品的研究者已发表的研究成果，覆盖表观转录组芯片、small RNA 修饰芯片、m6A 单碱基芯片、MeRIP-seq 与修饰相关产品线。
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| 文章标题 | 作者 | 期刊 | 年份 |
|---|---|---|---|
| CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma | Liu L, et al. | Molecular Cancer | 2022 |
| Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7 | Li K,et al | Molecular Cancer | 2023 |
| ADAT2-mediated A-to-I tRNA modification promotes oncogenic translation and colorectal cancer progression and chemoresistance | Hao Cheng, et al | Molecular Cancer | 2026 |
| TRMT6-mediated tRNA m1A modification acts as a translational checkpoint of histone synthesis and facilitates colorectal cancer progression | Chen N, et al | Nat Cancer | 2025 |
| The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway | Lin C, et al. | Molecular Cancer | 2022 |
| Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p | Yu Y Z, et al. | Molecular Cancer | 2022 |
| METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer | Wan W, et al. | Molecular Cancer | 2022 |
| METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis | Fan H N, et al. | Molecular Cancer | 2022 |
| Intranuclear paraspeckle-circular RNA TACC3 assembly forms RNA-DNA hybrids to facilitate MASH-related hepatocellular carcinoma growth in an m6A-dependent manner | Fu J, et al | Cancer Commun (Lond) | 2025 |
| Specific RNA m6A modification sites in bone marrow mesenchymal stem cells from the jawbone marrow of type 2 diabetes patients with dental implant failure | Yan W,et al | International Journal of Oral Science | 2023 |
| KIAA1429 promotes tumorigenesis and gefitinib resistance in lung adenocarcinoma by activating the JNK/ MAPK pathway in an m6A-dependent manner | Lin X,et al | Drug Resistance Updates | 2023 |
| o8G Site-Specifically Modified tRF-1-AspGTC: A Novel Therapeutic Target and Biomarker for Pulmonary Hypertension | Zhang J,et al | Circulation Research | 2024 |
| The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N 6-methyladenosine methylation of Parp10 mRNA | Gao X Q, et al. | Nature Cell Biology | 2020 |
| Therapeutic m6A Eraser ALKBH5 mRNA-Loaded Exosome−Liposome Hybrid Nanoparticles Inhibit Progression of Colorectal Cancer in Preclinical Tumor Models | Wu S,et al | ACS nano | 2023 |
| N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression | Dai Z, et al. | Molecular cell | 2021 |
| METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance. | Wang Q, et al. | Gut | 2019 |
| FTO-dependent m6A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke | Li B,et al | Nature Communications | 2023 |
| N7-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis | Han H, et al | Nature communications | 2022 |
| Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification | Xiong Y W,et al | Nature Communications | 2024 |
| N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration | Ma W, et al | Nature Communications | 2024 |
| RNA N6-methyladenosine modification-based biomarkers for absorbed ionizing radiation dose estimation | Chen H,et al | Nature Communications | 2023 |
| WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis | Li Z X, et al. | Cell Death & Differentiation | 2022 |
| ALKB-1-dependent tRNA methylation is required for efficient paternal mitochondrial elimination | Zhenhuan Luo, et al | nature communications | 2026 |
| β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer | Song P, et al. | Molecular Cancer | 2020 |
| m6A modification-mediated BATF2 acts as a tumor suppressor in gastric cancer through inhibition of ERK signaling | Xie J W, et al. | Molecular Cancer | 2020 |
| YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer | Li J, et al. | Molecular cancer | 2020 |
| The m7G Methyltransferase Mettl1 Drives Cardiac Hypertrophy by Regulating SRSF9-Mediated Splicing of NFATc4 | Yu S,et al | Advanced science | 2024 |
| SIRT1 regulates N6-methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2-dependent FTO SUMOylation | Liu X, et al. | Hepatology | 2020 |
| circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity | Li B, et al. | Nature communications | 2021 |
| METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs | Jin Y,et al | International Journal of Oral Science | 2024 |
| A Novel tsRNA, m7G-3′ tiRNA Lys TTT , Promotes Bladder Cancer Malignancy Via Regulating ANXA2 Phosphorylation | Ying X,et al | Advanced Science | 2024 |
| Sperm Rhoa m6A modification mediates intergenerational transmission of paternally acquired hippocampal neuronal senescence and cognitive deficits after combined exposure to environmental cadmium and high-fat diet in mice | Zhang J,et al | Journal of Hazardous Materials | 2023 |
| N6 -methyladenosine plays a dual role in arsenic carcinogenesis by temporal-specific control of core target AKT1 | Zhao T,et al | Journal of Hazardous Materials | 2022 |
| m5C-Modified tRF3b-Cys GCA -23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4 | Xiaoling Ying, et al | Advanced Science | 2026 |
| WDR5-H3K4me3 Epigenetic Axis Promotes TRMT6-Dependent tRNA M1A Modification to Facilitate Triple-Negative Breast Cancer Progression by Suppressing Ferroptosis | Lei Y, et al | Advanced Science | 2025 |
| Ythdc1-p300-Klf5 Complex-Mediated Golgi Dysfunction Promotes Aortic Aneurysm | Wen-Li Wang, et al | Advanced Science | 2025 |
| PGE2-EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase | Tao X, et al. | The EMBO Journal | 2022 |
| N6 -methyladenosine promotes aberrant redox homeostasis required for arsenic carcinogenesis by controlling the adaptation of key antioxidant enzymes | Zhao T,et al | Journal of Hazardous Materials | 2023 |
| ALKBH5 modulates COL5A1 mRNA stability via m6A demethylation to promote tobacco carcinogen NNK-induced lung cancer occurrence and progression | Du Y, et al | Journal of Advanced Research | 2025 |
| Mmu-LncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p /HtrA3 signaling axis | Pan J,et al | Molecular Therapy | 2022 |
| m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy | Cai D, et al | Journal of Experimental & Clinical Cancer Research | 2025 |
| METTL3-mediated pre-miR-665/DLX3 m6A methylation facilitates the committed differentiation of stem cells from apical papilla | Gu T,et al | Experimental & Molecular Medicine | 2024 |
| m7G-modified mt-tRF3b-LeuTAA regulates mitophagy and metabolic reprogramming via SUMOylation of SIRT3 in chondrocytes | Long D, et al | Biomaterials | 2024 |
| circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA | Ding L, et al. | Journal of Experimental & Clinical Cancer Research | 2022 |
| Glucose homeostasis controls N-acetyltransferase 10-mediated ac4C modification of HK2 to drive gastric tumorigenesis | Wang Q, et al | Theranostics | 2025 |
| N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration | Chen Z,et al | Cell Death & Differentiation | 2023 |
| The NAT10/c-Myc positive feedback loop orchestrates tRNA ac4C modiffcation and OTUB1-mediated protein stabilization to driveanaplastic thyroid carcinoma progression | Bo Wei,et al | Cellular & Molecular Biology Letters | 2026 |
| Adolescent co-exposure to environmental cadmium and high-fat diet induces cognitive decline via Larp7 m6A-mediated SIRT6 inhibition | Zhang J,et al | Journal of hazardous materials | 2024 |
| NADP modulates RNA m6A methylation and adipogenesis via enhancing FTO activity | Wang L, et al. | Nature Chemical Biology | 2020 |
| N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis | Chen R, et al. | Nature Communications | 2019 |
| Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis | Wu Y, et al. | Nature communications | 2019 |
| ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1 | Han Z, et al. | Theranostics | 2021 |
| N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1-Regulated Astrocyte Dysfunction and Depressive-like Behaviors. | Huang R, et al. | Biological Paychiatry | 2020 |
| METTL1-m7G-EGFR/EFEMP1 axis promotes the bladder cancer development | Ying X, et al. | Clinical and translational medicine | 2021 |
| WTAP/YTHDF1-mediated m6A modification amplifies IFN-γ-induced immunosuppressive properties of human MSCs | Chen Q,et al | Journal of Advanced Research | 2024 |
| N6-methyladenosine-modified circSLCO1B3 promotes intrahepatic cholangiocarcinoma progression via regulating HOXC8 and PD-L1 | Li J,et al | Journal of Experimental & Clinical Cancer Research | 2024 |
| METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma | Li H B, et al. | eBioMedicine | 2022 |
| METTL3 promotes colorectal carcinoma progression by regulating the m6A-CRB3-Hippo axis | Pan J, et al. | Journal of Experimental & Clinical Cancer Research | 2022 |
| RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent | Wang X, et al. | Journal of Experimental & Clinical Cancer Research | 2021 |
| Long-term cadmium exposure impairs cognitive function by activating lnc-Gm10532/m6A/FIS1 axis-mediated mitochondrial fission and dysfunction | Deng P,et al | Science of The Total Environment | 2022 |
| m6A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1 | Wu Y, et al | Molecular cancer | 2019 |
| KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3 | Lan T, et al. | Molecular Cancer | 2019 |
| The m5C methyltransferase NSUN2 promotes codon-dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer | Li P,et al | Clinical and Translational Medicine | 2023 |
| m6A-mediated regulation of PBX1-GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels | Liu Y, et al. | Cancer Communications | 2022 |
| KIAA1429-mediated M6A methylation inhibits osteoclast differentiation via stabilizing Lrp4 mRNA and protects against osteoporosis | Liu J, et al | Cell Mol Biol Lett | 2025 |
| Methyltransferase-like 3 leads to lung injury by up-regulation of interleukin 24 through N6-methyladenosine-dependent mRNA stability and translation efficiency in mice exposed to fine particulate matter 2.5 | He X, et al. | Environmental Pollution | 2022 |
| Combination of high-fat diet and cadmium impairs testicular spermatogenesis in an m6A-YTHDF2-dependent manner | Xiong Y W,et al | Environmental Pollution | 2022 |
| m6A modification of lncRNA PHKA1-AS1 enhances Actinin Alpha 4 stability and promotes non-small cell lung cancer metastasis | Guo Q,et al | MedComm | 2024 |
| M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression | Lv D, et al. | Oncogene | 2022 |
| METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth | Wu S,et al | Cancer letters | 2024 |
| m6A-modified circRNA MYO1C participates in the tumor immune surveillance of pancreatic ductal adenocarcinoma through m6A/PD-L1 manner | Guan H,et al | Cell Death & Disease | 2023 |
| The mechanism of BUD13 m6A methylation mediated MBNL1- phosphorylation by CDK12 regulating the vasculogenic mimicry in glioblastoma cells | Liu M,et al | Cell Death & Disease | 2022 |
| CircUGGT2 downregulation by METTL14-dependent m6A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR 186-3p/MAP3K9 axis | Chen X,et al | Pharmacological research | 2024 |
| Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infltration through the MLCK/p-MLC pathway | Xie Y,et al | Journal of Neuroinflammation | 2023 |
| N6-methyladenosine-modified SRPK1 promotes aerobic glycolysis of lung adenocarcinoma via PKM splicing | Wang A,et al | Cellular & Molecular Biology Letters | 2024 |
| LIN28B induced PCAT5 promotes endometrial cancer progression and glycolysis via IGF2BP3 deubiquitination | Wang B,et al | Cell Death & Disease | 2024 |
| N6-methyladenosine demethylase FTO regulates synaptic and cognitive impairment by destabilizing PTEN mRNA in hypoxic ischemic neonatal rats | Deng J,et al | Cell Death & Disease | 2023 |
| High glucose induces tau hyperphosphorylation in hippocampal neurons via inhibition of ALKBH5-mediated Dgkh m6A demethylation: a potential mechanism for diabetic cognitive dysfunction | Qu M,et al | Cell Death & Disease | 2023 |
| m6A RNA hypermethylation-induced BACE2 boosts intracellular calcium release and accelerates tumorigenesis of ocular melanoma | He F, et al. | Molecular Therapy | 2021 |
| The role of N6 -methyladenosine modification in benzene-induced testicular damage and the protective effect of melatonin | Han L,et al | Chemosphere | 2023 |
| Circular RNA circ-TNPO3 suppresses metastasis of gastric cancer by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL | Yu T, et al. | Molecular Therapy-Nucleic Acids | 2021 |
| ALKBH5-mediated m6A mRNA Methylation Governs Human Embryonic Stem Cell Cardiac Commitment | Han Z, et al. | Molecular Therapy-Nucleic Acids | 2021 |
| m6A methylation of precursor-miR-320/RUNX2 controls osteogenic potential of bone marrow-derived mesenchymal stem cells | Yan G, et al. | Molecular Therapy-Nucleic Acids | 2019 |
| METTL14 promotes tumorigenesis by regulating lncRNA OIP5-AS1/miR-98/ADAMTS8 signaling in papillary thyroid cancer | Zhang X, et al. | Cell Death & Disease | 2021 |
| RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes | Meng Y, et al. | Cell Death & Disease | 2021 |
| ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma | Yuan Y, et al. | Cell Death & Disease | 2021 |
| METTL3-mediated m6A modifcation of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing | Wang X,et al | Journal of Translational Medicine | 2023 |
| METTL3 and STAT3 form a positive feedback loop to promote cell metastasis in hepatocellular carcinoma | Liu B,et al | Cell Communication and Signaling | 2023 |
| The potential roles of m6A modification in regulating the inflammatory response in microglia | Li Q, et al. | Journal of Neuroinflammation | 2021 |
| N6 -methyladenosine-modifed circ_104797 sustains cisplatin resistance in bladder cancer through acting as RNA sponges | Xu C,et al | Cellular & Molecular Biology Letters | 2024 |
| N6-methyladenosine-modifed oncofetal lncRNA MIR4435-2HG contributed to stemness features of hepatocellular carcinoma cells by regulating rRNA 2′-O methylation | Zhu Y,et al | Cellular & Molecular Biology Letters | 2023 |
| De-succinylation-induced accumulation of TRMT10C in the nucleus plays a detrimental role in coronary microembolization via its m1A modification function | Chen H, et al | International Journal of Biological Sciences | 2025 |
| The m6A modification-mediated upregulation of ETS2 translation drives arsenic-induced spermatogonial senescence | Zhang X, et al | Free Radical Biology And Medicine | 2025 |
| FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12 | Chen Z, et al | cell death & disease | 2024 |
| The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network | Cheng M, et al. | Oncogene | 2019 |
| Linking oxysterols and different stages of mild cognitive impairment: insights from gut metabolites and N6-methyladenosine | Wen F, et al | Alzheimer's Research & Therapy | 2025 |
| N6-methyladenosine-mediated upregulation of LNCAROD confers radioresistance in esophageal squamous cell carcinoma through stabilizing PARP | Shi X, et al | Clinical And Translational Medicine | 2024 |
| Magnesium ions facilitate osteogenic differentiation and intervertebral fusion via m6A | Haocheng Xu, et al | Journal of Orthopaedic Translation | 2026 |
| Loss of m6A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury | Gong R, et al. | Pharmacological Research | 2021 |
| Aspergillus fumigatus Elongator complex subunit 3 affects hyphal growth, adhesion and virulence through wobble uridine tRNA modification | Zhang Y,et al | PLoS pathogens | 2022 |
| METTL4 mediated-N6-methyladenosine promotes acute lung injury by activating ferroptosis in alveolar epithelial cells | Sang A,et al | Free Radical Biology and Medicine | 2024 |
| Tumor-associated mesenchymal stem cells promote hepatocellular carcinoma metastasis via a DNM3OS/KDM6B/TIAM1 axis | Wang W, et al. | Cancer Letters | 2021 |
| CircUBXN7 promotes macrophage infiltration and renal fibrosis associated with the IGF2BP2-dependent SP1 mRNA stability in diabetic kidney disease | Lin Z,et al | Frontiers in Immunology | 2023 |
| The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis | Wang S, et al. | American Journal of Respiratory Cell and Molecular Biology | 2022 |
| Mettl14 Attenuates Cardiac Ischemia/Reperfusion Injury by Regulating Wnt1/β-Catenin Signaling Pathway | Pang P, et al. | Frontiers in cell and developmental biology | 2021 |
| Epitranscriptomic N4-acetylcytidine profiling in CD4+ T cells of systemic lupus erythematosus | Guo G,et al. | Frontiers in Cell and Developmental Biology | 2020 |
| Disease Activity-Associated Alteration of mRNA m5C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus | Guo G, et al. | Frontiers in Cell and Developmental Biology | 2020 |
| N6-methyladenosine modification of lnc-CCKAR-5 regulates autophagy in human umbilical cord mesenchymal stem cells by destabilizing LMNA and inhibits diabetic wound healing. | Wang J,et al | Journal of Investigative Dermatology | 2024 |
| WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis | Tan L,et al | Journal of Investigative Dermatology | 2023 |
| A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis | Hao R,et al | Cancer Cell International | 2023 |
| m6A reader IGF2BP2 promotes lymphatic metastasis by stabilizing DPP4 in papillary thyroid carcinoma | Wang W,et al | Cancer Gene Therapy | 2023 |
| N6-methyladenosine modification of circCUX1 confers radioresistance of hypopharyngeal squamous cell carcinoma through caspase1 pathway | Wu P, et al. | Cell Death & Disease | 2021 |
| Macrophage microvesicles-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury | Chen L,et al | The Journal of Physiology | 2023 |
| circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346 | Bai N, et al | Journal of Experimental & Clinical Cancer Research | 2018 |
| m6A mRNA methylation regulates the development of gestational diabetes mellitus in Han Chinese women | Wang J, et al. | Genomics | 2021 |
| M6A -mediated lncRNA SCIRT stability promotes NSCLC progression through binding to SFPQ and activating the PI3K/Akt pathway | Cheng Y, et al | Cellular and Molecular Life Sciences | 2025 |
| Sirt1 m6A modification-evoked Leydig cell senescence promotes Cd-induced testosterone decline | Zheng X, et al | Ecotoxicology and Environmental Safety | 2024 |
| MAZ-mediated N6-methyladenosine modification of ZEB1 promotes hepatocellular carcinoma progression by regulating METTL3 | Li D, et al | Journal of Translational Medicine | 2025 |
| LIN28A-dependent lncRNA NEAT1 aggravates sepsis-induced acute respiratory distress syndrome through destabilizing ACE2 mRNA by RNA methylation | Liu J, et al | Journal of Translational Medicine | 2025 |
| CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH | Xie L, et al | cell death discovery | 2024 |
| m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA | Wang H, et al | Cell & Bioscience | 2024 |
| YTHDC1 maintains trophoblasts function by promoting degradation of mA6-modified circMPP1 | Wang D,et al | Biochemical Pharmacology | 2023 |
| The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner | Chen X Y,et al | Frontiers in cell and developmental biology | 2021 |
| WTAP Function in Sertoli Cells Is Essential for Sustaining the Spermatogonial Stem Cell Niche | Jia G X, et al. | Stem Cell Reports | 2020 |
| Deep learning model and omics screening highlight angiotensinogen as a 5-methylcytosine (m<sup>5</sup>C) regulated mediator of tumor-microenvironment communication in liver cancer. | Huai Pang, et al | Frontiers in Immunology | 2026 |
| M6A RNA methylation-mediated TUG1 stability maintains mitochondrial homeostasis during kidney aging by epigenetically regulating PGC1-α expression | Zhu Y, et al | Antioxidants & Redox Signaling | 2024 |
| m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis | Cui Y,et al | Cancer Gene Therapy | 2022 |
| WTAP dysregulation-mediated HMGN3-m6A modification inhibited trophoblast invasion in early-onset preeclampsia | Bian Y,et al | The FASEB Journal | 2022 |
| N6-methyladenosine modification promotes hepatocarcinogenesis through circ-CDYL-enriched and EpCAM-positive liver tumor-initiating exosomes | Wei Y,et al | iScience | 2023 |
| LINC01605, regulated by the EP300-SMYD2 complex, potentiates the binding between METTL3 and SPTBN2 in colorectal cancer | Yue M，et al. | Cancer Cell International | 2021 |
| Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury | Zhao T X, et al. | Environmental Pollution | 2020 |
| Histone demethylase KDM6A promotes somatic cell reprogramming by epigenetically regulating the PTEN and IL-6 signal pathways | Jiang Q, et al. | STEM CELLS | 2020 |
| Exploring CircRNA N6-methyladenosine in human rheumatoid arthritis: Hyper-methylated hsa_circ_0007259 as a potential biomarker and its involvement in the hsa_circ_0007259/hsa_miR-21-5p/STAT3 axis | Luo H,et al | International Immunopharmacology | 2023 |
| Shikonin targets to m6A-modified oxidative damage pathway to alleviate benzeneinduced testicular injury | Han L,et al | Food and Chemical Toxicology | 2022 |
| ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation | He Y,et al | Cellular Physiology and Biochemistry | 2018 |
| AtTRM61/AtTRM6 complex is a bona fide tRNA N1-methyladenosine methyltransferase in Arabidopsis | Tang J, et al. | Journal of Experimental Botany | 2020 |
| TRMT10C-mediated m7G modification of circFAM126A inhibits lung cancer growth by regulating cellular glycolysis | Zhao Q, et al | Cell Biology and Toxicology | 2024 |
| circBRAF promotes the progression of triple-negative breast cancer through modulating methylation by recruiting KDM4B to histone H3K9me3 and IGF2BP3 to mRNA | Lan J,et al | American journal of cancer research | 2024 |
| Alteration of N6-Methyladenosine RNA Profiles in Cisplatin-Induced Acute Kidney Injury in Mice | Li C M, et al. | Frontiers in Molecular Biosciences | 2021 |
| The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m6A RNA methylation reading protein Ythdf2 | Yang Y, et al. | Cell Death Discovery | 2022 |
| tRF16 affects NFKBIA stability and promotes osteoarthritis progression by regulating ALKBH5 expression in m6A-dependent manner | Zhu C, et al | Communications Biology | 2025 |
| METTL3 modulates m6A modification of CDC25B and promotes head and neck squamous cell carcinoma malignant progression | Guo Y, et al. | Experimental hematology & oncology | 2022 |
| Long Noncoding RNA and mRNA m6A Modification Analyses of Periodontal Ligament Stem Cells from the Periodontitis Microenvironment Exposed to Static Mechanical Strain | Sun W,et al | Stem Cells International | 2022 |
| Recruitment of PVT1 Enhances YTHDC1-Mediated m6A Modification of IL-33 in Hyperoxia-Induced Lung Injury During Bronchopulmonary Dysplasia | Bao T,et al | Inflammation | 2023 |
| ALKBH5 Exacerbates Aortic Dissection by Promoting Inflammatory Response and Apoptosis of Aortic Smooth Muscle Cells via Regulating lnc-TMPO-AS1/EZH2/IRAK4 Signals in an m6A Modification Manner | Wang P, et al. | Oxidative Medicine and Cellular Longevity | 2021 |
| Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice | Wang Y, et al | Epigenomics | 2019 |
| Dynamic m6A Modification Landscape During the Egg Laying Process of Chickens | Zhang Y, et al | International Journal of Molecular Sciences | 2025 |
| Chronic Hexavalent Chromium Exposure Up-regulates the RNA Methyltransferase METTL3 Expression to Promote Cell Transformation, Cancer Stem Cell-like Property and Tumorigenesis | Wang Z, et al. | Toxicological Sciences | 2022 |
| Circular RNA 103862 Promotes Proliferation and Invasion of Laryngeal Squamous Cell Carcinoma Cells Through the miR-493-5p/GOLM1 Axis | Wang X, et al. | Frontiers in Oncology | 2020 |
| ALKBH5-mediated m6A regulates the alternative splicing events of SRSF10 in ovarian cancer | Li K, et al | Cancer Gene Therapy | 2025 |
| Advanced glycation end products alter the m6A-modified RNA profiles in human dermal fibroblasts | Ouyang M, et al. | Epigenomics | 2022 |
| Alteration of the m6A methylation landscape in a mouse model of scleroderma | Shen L, et al. | Epigenomics | 2021 |
| Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration | Wang X, et al. | Epigenomics | 2020 |
| Comprehensive analyses of molecular features, prognostic values, and regulatory functionalities of m6A-modifed long non-coding RNAs in lung adenocarcinoma | Zhang M,et al | Frontiers in Genetics | 2022 |
| circ_0103896/miR-432-5p/FTO feedback loop suppresses the formation and progression of intracranial aneurysm | Lu Z, et al | Non-coding RNA Research | 2025 |
| METTL3-m6A methylation inhibits the proliferation and viability of type II alveolar epithelial cells in acute lung injury by enhancing the stability and translation efficiency of Pten mRNA | Wang Q, et al | Respiratory research | 2024 |
| IGF2BP3 promotes gastric cancer progression by inhibiting ferroptosis through ETV4-mediated regulation of GCH1 | Kan Li , et al | Cancer Biology & Therapy | 2026 |
| Characterization of the Expressions and m6A Methylation Modification Patterns of mRNAs and lncRNAs in a Spinal Cord Injury Rat Model | Liu X,et al | Molecular neurobiology | 2024 |
| Exploring the Roles of m6A-Modifed circRNAs in Myasthenia Gravis Based on Multi-Omics Analysi | Li S,et al | Molecular Neurobiology | 2024 |
| DNA damage-mediated FTO downregulation promotes CRPC progression by inhibiting FOXO3a via an m6A-dependent mechanism | Xu L, et al | iScience | 2024 |
| Distinct N7-methylguanosine profles of circular RNAs in drug-resistant acute myeloid leukemia | Fu J,et al | Scientific Reports | 2023 |
| High-throughput microarray reveals the epitranscriptome-wide landscape of m6A-modified circRNA in oral squamous cell carcinoma | Zhao W,et al | BMC genomics | 2022 |
| The m6A reader IGF2BP1 attenuates the stability of RPL36 and cell proliferation to mediate benzene hematotoxicity by recognizing m6A modification | Wang J,et al | Toxicology | 2024 |
| N6-Methyladenosine RNA Modification Landscape in the Occurrence and Recurrence of Nasopharyngeal Carcinoma | Wang Y M,et al | World Journal of Oncology | 2022 |
| Alteration of N6-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy | Li X, et al. | Epigenomics | 2020 |
| N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1 | Xu L, et al | BMC Biology | 2025 |
| m6A demethylase Fto inhibited macrophage activation and glycolysis in diabetic nephropathy via m6A/Npas2/Hif-1α axis | Zhu S, et al | Faseb Journal | 2025 |
| Human m6A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease | Ruan H, et al. | Scientific Reports | 2021 |
| AQP3 Influences Unexplained Recurrent Abortion by Regulating Trophoblast Cell Migration and Invasion via the METTL14/IGF2BP1/AQP3/PI3K/AKT Pathway | Nong Y, et al | Journal of Cellular and Molecular Medicine | 2025 |
| METTL3-Mediated m6A Modification Regulates the Osteogenic Differentiation through LncRNA CUTALP in Periodontal Mesenchymal Stem Cells of Periodontitis Patients | Chen X,et al | Stem Cells International | 2024 |
| TRF-16 Inhibits Lung Cancer Progression by Hindering the N6-Methyladenosine Modification of CPT1A mRNA | Ye J, et al | Journal of Cellular And Molecular Medicine | 2024 |
| Splicing factor TRA2A contributes to esophageal cancer progression via a noncanonical role in lncRNA m6A methylation | Bei M, et al | Cancer Science | 2023 |
| Alteration of m6A epitranscriptomic tagging of ribonucleic acids after spinal cord injury in mice | Ni S,et al | Frontiers in Neuroscience | 2022 |
| Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing | Zhang Z, et al. | Epigenetics | 2020 |
| METTL3 promotes human amniotic epithelial stem cells differentiation into insulin-producing cells by regulation of MaFA expression | Luo Y, et al | Biochimica et Biophysica Acta-molecular Basis of Disease | 2025 |
| Analysis of N6-methyladenosine-modified mRNAs in diabetic cataract | Cai L,et al | World Journal of Diabetes | 2023 |
| Function and Prognostic Value of N6-Methyladenosine-modified RNAs in Lung Adenocarcinoma | Liu J,et al | The Journal of Gene Medicine | 2022 |
| N6-methyladenosine promotes osteogenic differentiation of PDLSCs from periodontitis patients | Zhang X,et al | Oral Diseases | 2022 |
| Alteration of the N6 -methyladenosine methylation landscape in a mouse model of polycystic ovary syndrome | Zou L,et al | Journal of Ovarian Research | 2023 |
| RNA N6-methyladenosine demethylase FTO inhibits glucocorticoid-induced osteoblast differentiation and function in bone marrow mesenchymal stem cells | Feng L,et al | Journal of Cellular Biochemistry | 2023 |
| Chronic allergic asthma alters m6A epitranscriptomic tagging of mRNAs and lncRNAs in the lung | Ni X,et al | Bioscience Reports | 2022 |
| Correlations of m6A methylation-related mRNAs with thyroid cancer | Jiang Z, et al | Sci Rep | 2026 |
| YTHDF2 is essential for spermatogenesis and fertility by mediating a wave of transcriptional transition in spermatogenic cells | Zhao X,et al. | Acta Biochimica et Biophysica Sinica | 2021 |
| Microarray analysis of genes with differential expression of m6A methylation in lung cancer | Wu S, et al. | Bioscience Reports | 2021 |
| WTAP promotes oesophageal squamous cell carcinoma development by decreasing CPSF4 expression in an m6A-dependent manner | Luo Q,et al | Medical Oncology | 2022 |
| LncRNA and mRNA m6A modification profile and functional network in sepsis-induced acute lung injury | Yanli Yang , et al | Experimental and Molecular Pathology | 2026 |
| m6A modifications of circular RNAs in ischemia-induced retinal neovascularization | Zhou Y,et al | International Journal of Medical Sciences | 2023 |
| The significance of m6A-circFOXK2 in CD4+T cells from patients with rheumatoid arthritis and circFOXK2 correlates with Th17 % and autophagy | Luo Q, et al | Journal of Translational Autoimmunity | 2025 |
| Transcriptome-wide m6A methylation profle reveals its potential role underlying drought response in wheat (Triticum aestivum L.) | Pan Y,et al | Planta | 2024 |
| Expression profiling of N6-methyladenosine modified circRNAs in acute myeloid leukemia | Issah M A, et al. | Biochemical and Biophysical Research Communications | 2022 |
| Severe Burn Injury Significantly Alters the Gene Expression and m6A Methylation Tagging of mRNAs and lncRNAs in Human Skin | Ran Y,et al | Journal of Personalized Medicine | 2023 |
| FTO promotes the progression of triple-negative breast cancer by regulating the m6A methylation of NFKBIE | Zhang J, et al | Clin Exp Med | 2025 |
| N6-methyladenosine modifications of mRNAs and long noncoding RNAs in oxygen-induced retinopathy in mice | Peng Y, et al. | Experimental Eye Research | 2022 |
| Fusarium infection alters the m6A-modified transcript landscape in the cornea | Jianzhang Hu,Yi Lin | Experimental Eye Research | 2020 |
| Comprehensive analysis of the transcriptome-wide m6A Methylome in sheep testicular development | Xi B, et al | Genomics | 2025 |
| RNAs m6A Modification Facilitates UVB-induced Photoaging | Zhang S, et sl | Heliyon | 2024 |
| ALKBH5 promotes colon cancer progression by decreasing methylation of the lncRNA NEAT1 | Guo T, et al. | American Journal of Translational Research | 2020 |
| FTO promotes cell proliferation and migration in esophageal squamous cell carcinoma through up-regulation of MMP13 | Liu S, et al. | Experimental Cell Research | 2020 |
| Comprehensive analysis of transcriptome-wide m6A methylome in intermediate-stage Esophageal squamous cell carcinoma | Jia X,et al | Pathology-Research and Practice | 2022 |
| FTO promotes ferroptosis through m6A-dependent downregulation of HSPG2 expression in endothelial cell metabolic memory and diabetic nephropathy | Nan Zhu, et al | Archives of Medical Science | 2026 |
| Dynamic alterations in m6A RNA methylation profiles during involution of infantile hemangiomas | Wu P, et al | Front Oncol | 2025 |
| M6A-dependent regulation of microRNAs from CKD stage 5 patients: insights from epigenetic modification analysis | Zhiqian Yang, et al | Epigenetics | 2026 |
| METTL16-mediated translation of CIDEA promotes non-alcoholic fatty liver disease progression via m6A-dependent manner | Tang J,et al | PeerJ | 2022 |
| METTL3 alleviates renal tubular mitochondrial dysfunction by regulating the TUG1/PGC-1a axis in an IGF2BP2-dependent manner in diabetic nephropathy | Chen T, et al | Renal Failure | 2025 |
| The m6A methyltransferase METTL3 affects autophagy and progression of nasopharyngeal carcinoma by regulating the stability of lncRNA ZFAS1 | Peng J, et al. | Infectious Agents and Cancer | 2022 |
| Circular RNA_101237 mediates anoxia/reoxygenation injury by targeting let-7a-5p/IGF2BP3 in cardiomyocytes | Gan J,et al. | International Journal of Molecular Medicine | 2019 |
| METTL3-induced lncARSR aggravates neuroblastoma tumorigenic properties through stabilizing PHOX2B | Meng X, et al | Pathology - Research and Practice | 2024 |
| Alteration of N6-methyladenosine Modification Profiles in the Neutrophilic RNA Following Ischemic Stroke | Fan J,et al | Neuroscience | 2024 |
| Epitranscriptomic profling of m6A RNA methylation in renal epithelial tubular cells stimulated with calcium oxalate crystals through microarray analysis | Yang B Y,et al | Urolithiasis | 2023 |
| METTL16 promotes corneal nerve regeneration in diabetic corneal neuropathy | Zhang Y, et al | Experimental Eye Research | 2025 |
| Epitranscriptomic Analysis of the Ventral Hippocampus in a Mouse Model of Post-Traumatic Stress Disorder Following Deep Brain Stimulation Treatment of the Basolateral Amygdala | Ma M, et al | brain science | 2025 |
| 5-MethylcytosineAnalysisofmiRNAsinMinimalChange Disease | Zeng H, et al | Biotechnol Appl Biochem | 2025 |
| Proteomic changes of the bilateral M1 and spinal cord in hemiplegic cerebral palsy mouse: Effects of constraint-induced movement therapy | Huang Y,et al | Behavioural Brain Research | 2023 |
| Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea | Lan J, et al | Bmc Pulmonary Medicine | 2025 |
| METTL3-mediated N6-methyladenosine modification of LEPR is critical for fetal growth restriction | Dianjie Li，et al | Placenta | 2026 |
| Overexpression of METTL3 in lung cancer cells inhibits radiation-induced bystander effect | Zhang Y, et al | Biochemical and Biophysical Research Communications | 2025 |
| Signatures of miRNA 5-methylcytosine modification profile and potential immune-related target gene regulation in diabetic kidney disease | Yang Z, et al | Gene | 2025 |
| Integrated analysis of the transcriptome-wide m6A methylome in preeclampsia and healthy control placentas | Wang J, et al. | PeerJ | 2020 |
| Synovial fluid-derived exosomal lncRNA PCGEM1 as biomarker for the different stages of osteoarthritis | Zhao Y, Xu J | International orthopaedics | 2018 |
| Epitranscriptome of the ventral tegmental area in a deep brain-stimulated chronic unpredictable mild stress mouse model | Song N, et al. | Translational Neuroscience | 2020 |
| N6-methyladenosine-modified miR-873 promotes receptor interacting protein kinase 3-mediated necroptosis after intracerebral hemorrhage in mice and HT22 cells | Jianfei Wang, et al | NeuroReport | 2026 |
| LncRNA SLC7A11-AS1 suppresses the ferroptosis of bladder cancer cells through regulating SLC7A11 by IGF2BP1 via m6A modification | Yu G, et al | Journal of Radiation Research and Applied Sciences | 2025 |
| Data set of m6A Methylation-Related RNAs from patients of papillary thyroid carcinoma without autoimmune thyroid disease | Lin Y, et al | Data in Brief | 2025 |
| Inhibition of the m6A Reader IGF2BP2 Impairs Cell Cycle Progression and Glycolysis in Ovarian Cancer | Liang J, et al | Molecular Biology | 2026 |
| circLPAR3 promotes the progression of papillary thyroid carcinoma through the IGF2BP2/TRIM55 axis | Kaiqing Liu, et al | Cell Investigation | 2026 |
| Cold exposure aggravates myocardial ischemia-reperfusion injury via m6A-mediated circRNA-mRNA regulatory networks | Wu Han, et al | Frigid Zone Medicine | 2026 |
| 低敲低Cav1基因可抑制小鼠肝细胞线粒体功能及关键基因基因可抑制小鼠肝细胞线粒体功能及关键基因 mRNA的的m6A修饰和表达 | 丁珊珊 | 南方医科大学学报 | 2025 |
| N6-methyladenosine-modified circRPS6KC1 regulated cell senescence in prostate cancer via FOXM1/PCNA axis | Shu X,et al | Research Square | 2024 |
| NSUN2通过m5C修饰介导系统性红斑狼疮患者中 CD4+ T细胞的活化 | 陈稳稳 等 | 温州医科大学学报 | 2024 |
| m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p | Wang K,et al | Research Square | 2024 |
| ALKBH5-dependent upregulation of circARHGEF12 by Oridonin impairs gastric cancer progression and cisplatin resistance via regulating miR-130b 5p/LATS2 signaling | Yang Y, et al | Reaearch Square | 2024 |
02怎么用这份清单
- 找先例。想知道某类修饰或某个研究体系有没有人做过，按标题逐个看，比从方法学文献入手更快。
- 找读数组合。注意一篇研究里修饰数据之外还配了什么读数，这类搭配往往可以直接借到自己的方案里。
- 找对照设计。看别人在同样的问题上怎么设分组与对照，再用到自己材料上时需要重新判断一次。
- 不必把清单当覆盖度证明。这里列的是已经发表的部分，尚未发表或未收录的工作不在这份清单里。
先看别人把同一类问题做到哪一步，再决定自己的实验要读到哪一层——已发表的研究是最好的起点，但它不替你做判断。Dominissini D. et al., Nature 2012 · DOI 10.1038/nature11112
03常见问题
清单里的文章是怎么选进来的？
按产品线与服务线筛选：只保留使用 RNA 修饰相关服务或产品的研究，通用表达谱、DNA 甲基化与不涉及修饰的测序不在其中。标题、作者、期刊与年份按发表时的记录列出，没有改写。
为什么按影响因子排序？
从高到低排能让高分期刊上的研究先被看到，在需要快速判断某类问题被做到什么程度时更省事。排序依据是收录时的影响因子，页面上不显示数值。
页面上的文章能下载吗？
页面只给出标题、作者、期刊与年份，便于检索；原文请通过期刊或文献数据库获取。我们不提供原文的转载。
我的文章用了你们的服务，能加进来吗？
可以。把文章信息与用到的服务线告诉我们，核对之后会补进清单。同一条研究如果用了多条服务线，会按服务线的实际使用情况登记。
清单里没有我关心的方向怎么办？
可以把关心的修饰类型或研究体系告诉我们。清单之外往往还有未发表的工作，能不能对到先例，可以在方案沟通时一并确认。