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单细胞测序技术服务 靶向lncRNA单细胞全转录组测序 单细胞全转录组测序 |
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生物分子凝聚体研究 HyPro靶RNA临近标记技术 |
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RNA-蛋白相互作用 HyPro - MS CHIRP – MS RNA pull-down MS |
RNA-RNA/DNA相互作用 HyPro-seq/芯片 CHIRP-seq |
蛋白-RNA相互作用 AGO APP seq/芯片 RIP-RNA seq/芯片 |
蛋白-蛋白相互作用 CoIP-MS |
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NGS测序技术服务 DRIPc-seq |
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NGS测序技术服务 环状DNA测序 |
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基因芯片技术服务 Small RNA修饰芯片 m6A单碱基分辨率芯片 mRNA&lncRNA表观转录组芯片 circRNA表观转录组芯片 |
NGS测序技术服务 表观转录组学测序服务 RNA m6A甲基化测序（MeRIP Seq） |
LC-MS mRNA碱基修饰检测 tRNA碱基修饰检测 |
PCR技术服务 MeRIP-PCR技术服务 m6A绝对定量RT-PCR技术服务 m6A单碱基位点PCR（MazF酶切法）技术服务 |
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NGS测序技术服务 ATAC-Seq DNA（羟）甲基化测序（抗体法） DNA甲酰基胞嘧啶(5fc)修饰测序 DNA 5hmC 测序（化学法） 染色质免疫共沉淀测序 |
PCR技术服务 MeDIP-qPCR hMeDIP-qPCR ChIP-qPCR |
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Ribo-seq Ribo seq |
核糖体-新生肽链复合物(RNC) RNC联合 circRNA芯片 RNC联合 lncRNA芯片 RNC联合mRNA-seq |
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , Molecular Cancer . 2022
N6 -methyladenosine plays a dual role in arsenic carcinogenesis by temporal-specific control of core target AKT1. Journal of Hazardous Materials. 2022
PGE2‐EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase. The EMBO Journal. 2022
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , Molecular Cancer . 2022
METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma. eBioMedicine. 2022
Methyltransferase-like 3 leads to lung injury by up-regulation of interleukin 24 through N6-methyladenosine-dependent mRNA stability and translation efficiency in mice exposed to fine particulate matter 2.5. Environmental Pollution. 2022
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer . Molecular Cancer . 2022
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis . Cell Death & Differentiation . 2022
METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis . Journal of Experimental & Clinical Cancer Research . 2022
m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels . Cancer Communications . 2022
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression . Oncogene . 2022
The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis . American Journal of Respiratory Cell and Molecular Biology . 2022
METTL3 modulates m6A modification of CDC25B and promotes head and neck squamous cell carcinoma malignant progression . Experimental hematology & oncology . 2022
Chronic Hexavalent Chromium Exposure Up-regulates the RNA Methyltransferase METTL3 Expression to Promote Cell Transformation, Cancer Stem Cell-like Property and Tumorigenesis . Toxicological Sciences . 2022
Advanced glycation end products alter the m6A-modified RNA profiles in human dermal fibroblasts . Epigenomics . 2022
Expression profiling of N6-methyladenosine modified circRNAs in acute myeloid leukemia . Biochemical and Biophysical Research Communications . 2022
